Abstract
Although intake of multivitamin supplements is becoming increasingly popular, the relationship between intake of multivitamin supplements and incident asthma remains unclear. Prospective studies in adults with long-term follow-up are especially scarce. Our objective was to investigate the association between intake of multivitamin supplements and asthma development in Norwegian adults.
We followed 16 952 adult subjects from the second survey of the Nord-Trøndelag Health Study (1995–1997) up to 2006–2008, who, at baseline, were free of asthma and provided information on their intake of multivitamin supplements and cod liver oil. Regular intake of multivitamin supplements or cod liver oil was defined as daily intake for ≥3 months during the year prior to baseline. Incident asthma was defined as reported new-onset asthma after the 11-year follow-up.
Intake of multivitamin supplements only was associated with an increased odds ratio for incident asthma (OR 1.55, 95% CI 1.12–2.13) after adjustment for a number of common confounding factors (model I). Similar odds ratios were found for intake of cod liver oil only and for intake of both supplements (1.59 and 1.73, respectively).
Regular intake of multivitamin supplements was associated with an increased odds ratio for incident asthma in Norwegian adults.
Abstract
Multivitamin supplement intake was associated with an increased odds ratio for incident asthma in Norwegian adults http://ow.ly/RNBxo
Footnotes
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Support statement: This study was supported by funds from the Research Council of Norway (project number 201895/V50). The Lung Study in HUNT 2 and HUNT 3 received funding from AstraZeneca Norway. B. Brumpton received a post-doctoral fellowship grant from the Liaison Committee between the Central Norway Regional Health Authority and the Norwegian University of Science and Technology. None of the funding sources was involved in any aspect of the study design, conduct, analysis, interpretation of data, or writing the report. Funding information for this article has been deposited with FundRef.
Conflict of interest: Disclosures can be found alongside this article at openres.ersjournals.com
- Received June 22, 2015.
- Accepted August 30, 2015.
- Copyright ©ERS 2015
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