RT Journal Article
SR Electronic
T1 Prevention of COPD exacerbations: medications and other controversies
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00011-2015
DO 10.1183/23120541.00011-2015
VO 1
IS 1
A1 Jørgen Vestbo
A1 Peter Lange
YR 2015
UL http://openres.ersjournals.com/content/1/1/00011-2015.abstract
AB Exacerbations have significant impact on the morbidity and mortality of patients with chronic obstructive pulmonary disease. Most guidelines emphasise prevention of exacerbations by treatment with long-acting bronchodilators and/or anti-inflammatory drugs. Whereas most of this treatment is evidence-based, it is clear that patients differ regarding the nature of exacerbations and are likely to benefit differently from different types of treatment. In this short review, we wish to highlight this, suggest a first step in differentiating pharmacological exacerbation prevention and call for more studies in this area. Finally, we wish to highlight that there are perhaps easier ways of achieving similar success in exacerbation prevention using nonpharmacological tools.More targeted pharmaceutical, and perhaps nonpharmaceutical, interventions are needed to prevent COPD exacerbation http://ow.ly/LQFcB