TY - JOUR T1 - Embolisation of PAVMs reported to improve nosebleeds by a subgroup of patients with hereditary haemorrhagic telangiectasia JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00035-2016 VL - 2 IS - 2 SP - 00035-2016 AU - Claire L. Shovlin AU - Trishan Patel AU - James E. Jackson Y1 - 2016/04/01 UR - http://openres.ersjournals.com/content/2/2/00035-2016.abstract N2 - Pulmonary arteriovenous malformations (PAVMs) are structurally abnormal vessels that provide direct capillary-free communications between the pulmonary and systemic circulations, and hence, right-to-left shunts [1]. Due to impaired gas exchange, hypoxaemia is common but exercise tolerance is usually preserved through haematological (erythrocytotic) and cardiovascular compensations [2, 3], and patients are frequently asymptomatic [1–3]. Treatment of PAVMs is recommended to prevent paradoxical embolic sequelae such as ischaemic strokes [4] and brain abscess [5], commonly improves migraine headaches [6], and is a successful emergency treatment for haemorrhage.Pulmonary AVM embolisation appears to improve nosebleed severity for nearly one in six people with HHT http://ow.ly/4mJqip ER -