@article {LamprouP13, author = {Kallirroi Lamprou and Ioanna Kechrimpari and Michael Georgoulis and Lazaros Paraskevopoulos and Emmanuel Vagiakis and Meropi Kontogianni and Nikos Yiannakouris}, title = {Relationship between food group consumption and biochemical characteristics of patients with obstructive sleep apnoea}, volume = {3}, number = {suppl 1}, elocation-id = {P13}, year = {2017}, doi = {10.1183/23120541.sleepandbreathing-2017.P13}, publisher = {European Respiratory Society}, abstract = {Background Obstructive Sleep Apnea (OSA) is characterized by an unfavorable cardiometabolic profile, including derangements of glucose metabolism indices and inflammatory pathways. Dietary habits may be associated with patients{\textquoteright} biochemical characteristics.Aims and objectives To investigate whether frequency of food group consumption is associated with clinical characteristics of OSA patients.Methods 134 individuals (76.1\% males, age: 49{\textpm}10y) with polysomnography-diagnosed OSA were included in the analysis. Nutritional assessment was performed using a food frequency questionnaire and food group consumption (servings/day) was evaluated. Lipid levels, glucose metabolism indices (insulin, HOMA-IR) and inflammation markers (TNF-a and adiponectin) were measured, using appropriate assays in fasting blood samples.Results TNF-a levels were negatively correlated with whole grain and legume consumption (rho=-0,264, P=0,027 and rho=-0,321, P=0,007, respectively). In addition, a significant negative correlation was observed between adiponectin levels and red meat consumption (rho=-0,322, P=0,007). Finally, HOMA-IR index was positively correlated with refined grain, red meat and soft drink consumption (rho=0,212, P=0,040, rho=0,232, P=0,024, and rho=0,207, P=0,045, respectively). No association was found between fasting lipid levels and food group consumption.Conclusions Increased whole grain and legume consumption and reduced red meat consumption exhibit anti-inflammatory effects, whereas increased refined grain, red meat and soft drink consumption is associated with insulin resistance in OSA patients.}, URL = {https://openres.ersjournals.com/content/3/suppl_1/P13}, eprint = {https://openres.ersjournals.com/content}, journal = {ERJ Open Research} }