TY - JOUR T1 - Anthropometric, sleep and clinical characteristics of patients with obesity hypoventilation syndrome in comparison with obese obstructive sleep apnoea syndrome patients and controls JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.sleepandbreathing-2017.P94 VL - 3 IS - suppl 1 SP - P94 AU - Rodopi Sotiropoulou AU - Evangelia Nena AU - Christina Nikolaou AU - Afroditi Rousanidou AU - Ioannis Katrachouras AU - Andrea Kizi AU - Athanasios Voulgaris AU - Maria Xanthoudaki AU - Marios Froudarakis AU - Paschalis Steiropoulos Y1 - 2017/04/01 UR - http://openres.ersjournals.com/content/3/suppl_1/P94.abstract N2 - Aim of the study was to evaluate anthropometric, clinical and sleep characteristics of Obesity Hypoventilation Syndrome (OHS) patients, in comparison to obese eucapnic Obstructive Sleep Apnea Syndrome (OSAS) patients and controls.Methods Included were 942 consecutive subjects with BMI≥30kg/m2(69.9% males, age 54.9±11.9 years), examined with polysomnography (PSG), due to suspected OSAS. All had undergone pulmonary function testing and ABGs examination and had completed the Epworth Sleepiness Scale (ESS) and Athens Insomnia Scale (AIS) for sleepiness and insomnia assessment, respectively. They were categorized as follows: OHS patients (n=177), obese, eucapnic OSAS patients (AHI≥5/h, n=615), and obese controls with AHI<5/h (n=150).Results OHS patients had the highest BMI (p<0.001) and neck circumference measurements (p<0.001), but no difference was observed in other anthropometrics. Differences were observed in FVC, FEV1,SpO2, PaO2, PaCO2and HCO3values in awake (p<0.001 for all). PSG revealed a lower percentage of REM sleep (p=0.041) and a shorter REM latency (p=0.033) in OHS patients. AHI, ODI, minSpO2and averSpO2during sleep were more impaired in OHS patients (p<0.001). A higher prevalence of insomnia was observed in OHS (84.2%), followed by OSAS (70.8%) and controls (55.2%), p=0.041. Likewise, prevalence of daytime sleepiness was higher in OHS (59.2%) followed by OSAS patients (45.5%) and controls (32%), p<0.001.Conclusions OHS patients were more obese, differed significantly in several sleep characteristics and reported insomnia and daytime sleepiness more frequently, compared with obese OSAS patients and controls. ER -