RT Journal Article SR Electronic T1 Maintenance of Wakefulness Test in clinical practice JF ERJ Open Research JO erjor FD European Respiratory Society SP P5 DO 10.1183/23120541.sleepandbreathing-2017.P5 VO 3 IS suppl 1 A1 Leonor Meira A1 Mafalda van Zeller A1 Ermelinda Eusébio A1 Elizabete Santa Clara A1 Paulo Viana A1 Marta Drummond YR 2017 UL http://openres.ersjournals.com/content/3/suppl_1/P5.abstract AB I: Maintenance of Wakefulness Test (MWT) is used in the study and evaluation of patients with excessive daytime sleepiness and in those whose professional activity requires the ability to stay awake, for safety reasons.A: Characterization of patients submitted to MWT.M: Patients followed in the Respiratory Sleep Pathology outpatient clinic of a tertiary hospital in Portugal, who performed MWT between 2012-2015 where included.R: 23 male patients performed MWT, median age 47 yrs old (IQR 13). All were diagnosed with Sleep Apnoea Syndrome (SAS), 4 by PSG level I and the remaining by PSG level III, with median ESS 13.0 (IQR 12.5) and AHI 27.6/h (IQR 42.3), with good adherence to treatment (Positive Airway Pressure). 16 were professional drivers, 56.5% had smoking history and 60.9% had at least one cardiovascular risk factor. Regarding MWT's results, the median mean sleep latency was 21.9 minutes (IQR 22.2), 11 patients fell asleep in the four epochs and only 4 didn't sleep in any. Ten patients (43.5%) presented pathological sleepiness criteria (PSC). When comparing patients with and without PSC, no statistically significant differences were found regarding age, BMI, IAH, desaturation index or ESS. Four patients with ESS less than 15 had PSC in the MWT. 3 patients were temporarily prohibited to drive and saw their ventilator parameters adjusted, 3 were totally prohibited to drive and 1 saw his ventilator parameters adjusted.C: MWT is a useful test to evaluate daytime hypersomnia, particularly in patients with professional high-risk, especially those whose symptoms are underestimated. MWT's results didn't correlate with the severity of SAS, demographic characteristics or ESS. The authors emphasise its importance to decide on patient's ability to drive.