RT Journal Article
SR Electronic
T1 Effect of age on clinical and polysomnographic characteristics in patients with obstructive sleep apnoea syndrome (OSAS)
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP P51
DO 10.1183/23120541.sleepandbreathing-2017.P51
VO 3
IS suppl 1
A1 Izolde Bouloukaki
A1 Charalampos Mermigkis
A1 Eleni Pouladaki
A1 Rodanthi Pateli
A1 Manolis Markakis
A1 Violeta Moniaki
A1 Eleni Mauroudi
A1 Sophia Schiza
YR 2017
UL http://openres.ersjournals.com/content/3/suppl_1/P51.abstract
AB Background There is limited data on clinical and polysomnographic characteristics in patients with obstructive sleep apnea syndrome (OSAS) in different age groups.Objectives To investigate possible influence of age on sleep architecture and daytime sleepiness in a large sample of OSAS patients.Methods We enrolled 2399 patients with OSAS (apnea-hypopnea index, AHI≥5) divided into two age groups: over 65 (n=1180, mean age 70.2±4.5 years), and 65 or under (n=1219, mean age 50.1,±10.9 years). Subjective daytime sleepiness, reflected by the Epworth sleepiness scale (ESS), and polysomnographic parameters were recorded and compared between the two groups.Results There were no significantly differences regarding gender, BMI, daytime sleepiness (31.9% vs 46.7% had ESS›10) between the elderly and younger patients with OSAS, but the incidence of comorbidities such as hypertension and other cardiovascular diseases was significantly higher (p<0.001). The sleep architecture was significantly worse in elderly OSAS patients with lower SE (%) (p<0.001), REM (%) (p<0.001), and higher NREM (%) and WASO (p<0.001) compared with the younger patients. The percentage of SWS, apnea hypopnea index (AHI), and oxygen desaturaion index (ODI) had no significantly difference in the two groups. The mean and the lowest oxygen saturation and arousal index were significantly decreased in elderly OSAS patients (p<0.001).Conclusions Our results suggest that objective sleep quality was more impaired in elderly compared to younger-aged patients. Additionally the prevalence of sleepiness in the elderly group was low and elderly had more cardiovascular comorbidities.