@article {SpinziaP46, author = {Alessia Spinzia and Francesco Lagan{\`a} and Alessandra Ferrari and Mario Ziola}, title = {Maxillo-mandibular advancement in OSAS: an evidence based therapeutic procedure}, volume = {3}, number = {suppl 1}, elocation-id = {P46}, year = {2017}, doi = {10.1183/23120541.sleepandbreathing-2017.P46}, publisher = {European Respiratory Society}, abstract = {A lot of authors stated that surgical treatments in OSAS remain controversial, mainly because controlled studies and standardized criteria to define surgical efficacy are lacking. These considerations are debatable regarding the maxillo-mandibular advancement (MMA) procedure, that nowadays is the most powerful therapeutic option to treat patients with OSAS, with a strong rationale that supports indications and results.The surgical indications for MMA in the OSAS in adults are linked to an accurate diagnosis based on international guidelines. We claim that MMA is at least as effective as CPAP in the reduction of the apnoic obstructive events in OSAS. MMA has an immediate therapeutic effect, obtained in one surgical operation and stable with time. Fourty patients was treated with MMA a few minor complications (transitory trigeminal impairment, plates exposure and surgical access dehiscence) were not considered serious with severe or moderately severe OSAS who in terms of quality of life and cost-effectiveness by patients managed able to stop CPAP.The therapeutic solution of MMA proposed by the maxillofacial surgeon aims to re-establish a better anatomy with no damage for the organs involved in OSAS. If planned and carried out adequately, MMA can lead to a nearly 100\% cure of OSAS. Accordingly, the use of MMA is the surgical treatment of choice in OSAS, instead of using it only for severe cases or after the failure of additional surgical procedures, among patients with or without important maxillomandibular dismorphosis.}, URL = {https://openres.ersjournals.com/content/3/suppl_1/P46}, eprint = {https://openres.ersjournals.com/content}, journal = {ERJ Open Research} }