RT Journal Article SR Electronic T1 Developing a comprehensive sleep programme at a public health hospital to enhance treatment of sleep apnoea JF ERJ Open Research JO erjor FD European Respiratory Society SP P40 DO 10.1183/23120541.sleepandbreathing-2017.P40 VO 3 IS suppl 1 A1 Maria Victorina Lopez Varela A1 Cecilia Rodriguez A1 Edilberto Pacheco A1 Carolina Silva A1 Karina Fagundez A1 Eric Gimenez A1 Ana Lia Tempone YR 2017 UL http://openres.ersjournals.com/content/3/suppl_1/P40.abstract AB Continuous positive airway pressure (CPAP) is standard therapy for Obstructive Sleep Apnea Syndrome (OSAS). Correct and frequent use is essential. We developed a comprehensive Sleep Program providing diagnosis, CPAP, education and follow-up.Objectives Evaluate CPAP adherence and factors associated.Methods OSAS patients (2006-2016) under Hospital care coverage CPAP prescription were titrated, trained and scheduled follow up. Symptoms, co-morbidities, anthropometry, PSG, CPAP use, follow-up, adherence, related benefit were recalled comparing 2 groups: 1 good CPAP adherence (4/more hours night) and 2 poor adherence.Results 335 OSAS patients, 84,4% good adherence (group 1) compared to group 2 NS difference in: age 56,9±10, 1 years vs 54,6±9,3, gender 55,8% females vs 68,4, BMI 40,4±10,2 vs 40,7±12.5, hypertension 71,1 vs 63,2% ,diabetes 43,8 vs 26,3% hypothyroidism 19.6 vs 15,8 % EPW (Epworth scale)7,9±5,6 vs 6,9±6,3, snoring 61,0 vs 63,2%, observed apneas 45,6 vs 57,9%, IAH 43,8±28, 7 vs 37,8±19,8, titrated pressure 10,0±1, 5 vs 10,0±1,1. Group 1 differs to 2: anxiety/depression medication 25,3 vs 10,5% p<0,05, CPAP hours per night 6,6±1,6 vs 2,3±1,0 p<0,01, benefit 91,8 vs 52,6% p< 0,05 follow-up visits 6,4±3,8 vs 2,7±2,3 p<0,01. Multivariate model to explain CPAP adherence included: EPW, observed apneas, snoring, AHI, anxiety/depression, diabetes and hypothyroidism.Conclusions Comprehensive Sleep Program results in 6.6 hours/night CPAP use in 84.4% of patients. Adherence related to symptoms, severity, co-morbid conditions.