PT - JOURNAL ARTICLE AU - Anna R. Jackson AU - James H. Hull AU - James G. Hopker AU - John W. Dickinson TI - Impact of detecting and treating exercise-induced bronchoconstriction in elite footballers AID - 10.1183/23120541.00122-2017 DP - 2018 Apr 01 TA - ERJ Open Research PG - 00122-2017 VI - 4 IP - 2 4099 - http://openres.ersjournals.com/content/4/2/00122-2017.short 4100 - http://openres.ersjournals.com/content/4/2/00122-2017.full SO - erjor2018 Apr 01; 4 AB - Our aim was to evaluate the prevalence of exercise-induced bronchoconstriction (EIB) in elite football players and assess subsequent impact of therapy on airway health and exercise performance.97 male professional football players completed an airway health assessment with a eucapnic voluntary hyperpnoea (EVH) challenge to diagnose EIB. Players demonstrating a positive result (EVH+) were prescribed inhaler therapy depending on severity, including inhaled corticosteroids and inhaled short-acting β2-agonists, and underwent repeat assessment after 9 weeks of treatment. Eight players (EVH+ n=3, EVH− n=5) completed a peak oxygen uptake (V′O2peak) test at initial and follow-up assessment.Out of the 97 players, 27 (28%) demonstrated a positive EVH result. Of these, 10 had no prior history (37%) of EIB or asthma. EVH outcome was not predictable by respiratory symptoms. Seven (24%) of the 27 EVH+ players attended follow-up and demonstrated improved post-challenge spirometry (forced expiratory volume in 1 s pre-test −22.9±15.4%, post-test −9.0±1.6%; p=0.018). At follow-up V′O2peak improved by 3.4±2.9 mL·kg−1·min−1 in EVH+ players compared to 0.1±2.3 mL·kg−1·min−1 in EVH− players. Magnitude of inference analysis indicated treatment was possibly beneficial (74%) for exercise capacity.Elite football players have a high EIB prevalence. Treatment with inhaler therapy reduces EIB severity.Screening and treating EIB in elite football players improves airway health and may improve exercise performance http://ow.ly/ngE530iWGJh