TY - JOUR T1 - Hypersensitivity pneumonitis in fish processing workers diagnosed by inhalation challenge JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00071-2018 VL - 4 IS - 4 SP - 00071-2018 AU - Gro Tjalvin AU - Øistein Svanes AU - Randi Jacobsen Bertelsen AU - Bjørg Eli Hollund AU - Tor B. Aasen AU - Cecilie Svanes AU - Jorunn Kirkeleit Y1 - 2018/10/01 UR - http://openres.ersjournals.com/content/4/4/00071-2018.abstract N2 - Workers in the fish processing industry have increased risk of developing respiratory diseases due to occupational exposure to bioaerosols and related allergens [1–4]. The literature reports more occupational asthma in workers handling salmon [2, 5], and an exposure–response relationship between total protein exposure and cross-shift changes in forced expiratory volume in 1 s (FEV1) and lower respiratory tract symptoms [6]. To our knowledge, there are no published reports on hypersensitivity pneumonitis from this industry. Hypersensitivity pneumonitis is a complex disease for which there are no generally accepted diagnostic criteria, particularly at earlier stages of the disease. We present the case of a fish processing worker diagnosed with hypersensitivity pneumonitis caused by proteins from salmon, in which the aetiology was established using specific inhalation challenge (SIC) as a diagnostic tool.Hypersensitivity pneumonitis may be caused by occupational exposure in the fish processing industry http://ow.ly/GbEf30lFnykLene Svendsen (Dept of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway) performed the lung function measurements and Gaute Wathle (Dept of Radiology, Haukeland University Hospital, Bergen, Norway) contributed to the discussion of the HRCT of the lungs. ER -