PT - JOURNAL ARTICLE AU - Manuela Carugati AU - Stefano Aliberti AU - Luis Felipe Reyes AU - Ricardo Franco Sadud AU - Muhammad Irfan AU - Cristina Prat AU - Nilam J. Soni AU - Paola Faverio AU - Andrea Gori AU - Francesco Blasi AU - Marcos I. Restrepo ED - , TI - Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study AID - 10.1183/23120541.00096-2018 DP - 2018 Oct 01 TA - ERJ Open Research PG - 00096-2018 VI - 4 IP - 4 4099 - http://openres.ersjournals.com/content/4/4/00096-2018.short 4100 - http://openres.ersjournals.com/content/4/4/00096-2018.full SO - erjor2018 Oct 01; 4 AB - This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines.This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015.In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01).Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.Testing practices vary based on geography and disease severity, and IDSA/ATS/ERS testing recommendations are rarely followed http://ow.ly/80Iy30lxo1c