RT Journal Article
SR Electronic
T1 Randomised controlled trial of cognitive behavioural therapy in COPD
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00094-2018
DO 10.1183/23120541.00094-2018
VO 4
IS 4
A1 Karen Heslop-Marshall
A1 Christine Baker
A1 Debbie Carrick-Sen
A1 Julia Newton
A1 Carlos Echevarria
A1 Chris Stenton
A1 Michelle Jambon
A1 Joanne Gray
A1 Kim Pearce
A1 Graham Burns
A1 Anthony De Soyza
YR 2018
UL http://openres.ersjournals.com/content/4/4/00094-2018.abstract
AB Anxiety is an important comorbidity in chronic obstructive pulmonary disease (COPD). We investigated if cognitive behavioural therapy (CBT), delivered by respiratory nurses, reduced symptoms of anxiety and was cost-effective.Patients with COPD and anxiety were randomised to CBT or self-help leaflets. Anxiety, depression and quality of life were measured at baseline, 3, 6 and 12 months. A cost-effectiveness analysis was conducted from a National Health Service hospital perspective and quality-adjusted life-years estimated using the EuroQol-5D questionnaire.In total, 279 patients were recruited. Group mean change from baseline to 3 months in the Hospital Anxiety and Depression Anxiety Subscale was 3.4 (95% CI 2.62–4.17, p<0.001) for the CBT group and 1.88 (95% CI 1.19–2.55, p<0.001) in the leaflet group. The CBT group was superior to leaflets at 3 months (mean difference in the Hospital Anxiety and Depression Anxiety Subscale was 1.52, 95% CI 0.49–2.54, p=0.003). Importantly, the CBT intervention was more cost-effective than leaflets at 12 months, significantly lowering hospital admissions and attendance at emergency departments.CBT delivered by respiratory nurses is a clinically and cost-effective treatment for anxiety in patients with COPD relative to self-help leaflets.Cognitive behavioural therapy (CBT) delivered by respiratory nurses is clinically effective and cost-effective for patients with chronic obstructive pulmonary disease and symptoms of anxiety http://ow.ly/o41o30msBNy