Maternal characteristics associated with moderate or severe asthma exacerbations during pregnancy
| Exacerbation | No exacerbation | p-value | Relative risk (95% CI) | |
| Subjects n | 41 | 148 | ||
| Maternal age years | 25.9±5.8 | 26.2±5.6 | 0.795 | 0.99 (0.95–1.04) |
| BMI kg·m−2 | 29.1±7.5 | 28.3±7.2 | 0.536 | 1.01 (0.98–1.05) |
| BMI category | 0.701 | |||
| Normal weight | 17 (41.5) | 59 (39.9) | Reference | |
| Overweight | 8 (19.5) | 38 (25.7) | 0.78 (0.37–1.66) | |
| Obese | 16 (39.0) | 51 (34.5) | 1.07 (0.59–1.94) | |
| Weight gain during pregnancy kg | 9.8±7.2 | 11.0±6.5 | 0.273 | 0.98 (0.93–1.02) |
| Parity | 0.699 | |||
| 0 | 18 (43.9) | 60 (40.5) | 0.90 (0.52–1.55) | |
| ≥1 | 23 (56.1) | 88 (59.5) | ||
| Smoking status | 0.557 | |||
| Never/former smoker | 29 (70.7) | 99 (66.9) | Reference | |
| Quit smoking during pregnancy | 3 (7.3) | 20 (13.5) | 0.58 (0.19–1.73) | |
| Current smoker | 9 (22.0) | 29 (19.6) | 1.05 (0.54–2.01) | |
| Baseline ICS use | 0.155 | |||
| Yes | 17 (41.5) | 44 (29.7) | 1.49 (0.87–2.55) | |
| No | 24 (58.5) | 104 (70.3) |
Data are presented as mean±sd or n (%), unless otherwise stated. BMI: body mass index; ICS: inhaled corticosteroid.