TABLE 3

Patient characteristics

SuccessFailurep-value+
Subjects2710
Male/female17/105/50.71
Age years30.9±17.228.4±9.50.67
Genotype0.50
 F508del homozygous10 (37)6 (60)
 F508del heterozygous15 (55.6)4 (40)
 Other2 (7.4)0
Pancreatic insufficiency21 (77.8)9 (90)0.65
CF-related diabetes6 (22.2)3 (30)0.68
FEV1 % predicted66.9±24.161.5±18.20.57
Pseudomonas aeruginosa#22 (81.5)8 (80)0.92
Duration of infection weeks 3.7±6.62.6±3.10.60
MRSA carrier nasal/skin swabs4 (14.8)6 (60)0.03
  • Data are presented as n, mean±sd or n (%). CF: cystic fibrosis; FEV1: forced expiratory volume in 1s; MRSA: methicillin-resistant Staphylococcus aureus. #: chronic colonisation; : interval between first positive culture and start of eradication; +: Chi-squared (Fisher's exact test where appropriate) or t-test.