Functional annotation of the gene clusters
| Cluster | Genes in cluster | Function derived from Pathway Enrichment and Gene Ontology analyses | Gene list |
| 0 | 6 | TLR signalling: unfolded protein response | DNAJB1, DNAJC5B, HSPA1A, HSPB1, SAA1, TLR2 |
| 10 | 2 | TLR signalling | CD86, CXCL9 |
| 1 | 6 | Chemokines: signalling | CCL17, CCL22, CCL4, CCR1, CXCL13, CXCL5 |
| 7 | 3 | Chemokines: activity | CCL2, CCL3, CCL7 |
| 11 | 2 | Chemokines: NOD-like receptor signalling | CXCL1, CXCL2 |
| 2 | 5 | Muscle contraction | ACTN2, MYH6, MYL1, TCAP, TNNI3 |
| 3 | 5 | Integrins | CD14, ITGAM, ITGAX, ITGB2, SPON2 |
| 4 | 4 | Circadian clock | ARNTL, DBP, NR1D1, PER1 |
| 5 | 3 | Osteoclast differentiation | CLEC5A, TREM2, TYROBP |
| 6 | 3 | Interleukins: FC-epsilon receptor I signalling | FCER1G, FCGR2B, IL12B |
| 14 | 2 | Interleukins | IL1R2, IL1RN |
| 8 | 3 | p53 pathway | IGF1, IGFBP3, IGFBP6 |
| 9 | 3 | – | AHRR, ARNT2, MAFB |
| 12 | 2 | Class I MHC mediated antigen processing and presentation | CYBA, NCF4 |
| 13 | 2 | Immune response (complement pathway) | C1QA, C1QB |
| 15 | 2 | Glutathione metabolism | GCLC, GCLM |
| 16 | 2 | Heterotrimeric G-protein signalling pathway-Gq alpha and Go alpha mediated pathway | RGS1, RGS16 |
There were no pathways or processes significantly represented by cluster 9. TLR: Toll-like receptor; NOD: nucleotide-binding oligomerisation domain; MHC: major histocompatibility complex.