TABLE 2

Correlations between serum biomarkers and 6 month change in physiological parameters

6month change in FVC % predicted6month change in DLCO % predicted
rsp-valuersp-value
First time point
 Serum KL-6−0.250.07−0.130.36
 Serum SP-D−0.090.51−0.070.63
6month change
 Serum KL-6−0.38<0.01−0.330.01
 Serum SP-D−0.37<0.01−0.140.32

FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; KL-6: Krebs von den Lungen-6; SP-D: surfactant protein-D.