Univariate and multivariate models
| Model | Pneumococcal infection | Invasive pneumococcal infection | ||
| Coefficient (95% CI) | p-value | Coefficient (95% CI) | p-value | |
| Univariate | ||||
| SO2 | 1.411 (0.94–1.881) | <0.0001 | 0.243 (0.088–0.398) | 0.002 |
| CO | 9.303 (0.956–17.651) | 0.03 | ||
| O3 | −0.08 (−0.115– −0.044) | <0.0001 | ||
| NOx | 0.103 (0.078–0.127) | <0.0001 | 0.009 (0.0003–0.018) | 0.04 |
| NO | 0.261 (0.198–0.323) | <0.0001 | 0.025 (0.002–0.048) | 0.04 |
| NO2 | 0.208 (0.152–0.265) | <0.0001 | ||
| PM1 | −0.146 (−0.247– −0.045) | 0.005 | ||
| PM2.5 | −0.122 (−0.2– −0.044) | 0.002 | ||
| PM10 | −0.121 (−0.201– −0.04) | 0.004 | ||
| Relative humidity | −0.119 (−0.189– −0.05) | 0.001 | ||
| Temperature | −0.456 (−0.546– −0.367) | <0.0001 | −0.073 (−0.108– −0.038) | <0.0001 |
| Solar radiation | −0.029 (−0.039– −0.019) | <0.0001 | −0.004 (−0.008– −0.001) | 0.008 |
| Multivariate | ||||
| SO2 | 0.732 (0.342–1.121) | 0.0003 | 0.158 (−0.005–0.322) | 0.058 |
| Temperature | −0.196 (−0.326– −0.065) | 0.003 | −0.052 (−0.090– −0.014) | 0.008 |
| Relative humidity | −0.054 (−0.105– −0.002) | 0.04 | ||
| NO | 0.139 (0.065–0.212) | 0.0003 | ||
PMx: particles with a 50% cut-off aerodynamic diameter of x μm.