TABLE 1

Baseline characteristics of patients with idiopathic pulmonary fibrosis with or without lung cancer diagnosis during follow-up periods

CharacteristicsAll patientsPatients with lung cancerPatients without lung cancerp-value
Patients63270562
Age years69.5±8.566.8±7.969.8±8.50.006
Males %76.494.374.2<0.001
BMI kg·m−223.2±3.123.2±2.923.2±3.10.996
Smoking exposure pack-years35.0 (0–141)46.4 (0.75–120)31.0 (0–141)<0.001
Smokers %76.410073.5<0.001
Emphysema %29.760.026.0<0.001
FVC % pred76.2±20.289.2±16.975.1±20.1<0.001
FEV1/FVC %80.3±10.874.1±9.480.9±10.7<0.001
DLCO % pred76.4±23.574.9±26.976.6±23.20.517
PaO2 mmHg74.0±15.177.3±12.273.5±15.40.194
ESR mm·h−134.0 (2–138)36.5 (5–120)34.0 (2–138)0.665
CRP mg·dL−10.24 (0.00–50.68)0.29 (0.00–15.11)0.23 (0.00–50.68)0.819
Albumin g·dL−14.0±0.54.0±0.44.0±0.50.763
KL-6 U·mL−1762.0 (149–9705)649.5 (347–2454)775.0 (149–9705)0.078

Data are presented as mean±sd or median (range), unless otherwise stated. BMI: body mass index; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; PaO2: arterial oxygen tension; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; KL: Krebs von der Lungen. p-values were calculated in relation to with or without lung cancer diagnosis.