TABLE 3

Distribution of study design, sample size and main outcome by the evaluated journals

AJRCCMERJChestThoraxNEJM+LancetSelected medical journalsAll articles
Total articles n40404040320360840
Study design
  •  Cross-sectional survey

14 (35.0)10 (25.0)10 (25.0)12 (30.0)43 (13.4)107 (29.7)196 (23.3)
  •  Longitudinal cohort study

14 (35.0)10 (25.0)11 (27.5)10 (25.0)49 (15.3)62 (17.2)156 (18.6)
  •  Case–control

4 (10.0)7 (17.5)3 (7.5)3 (7.5)7 (2.2)18 (5.0)42 (5.0)
  •  Interventional study (clinical trial)

3 (7.5)7 (17.5)6 (15.0)11 (27.5)173 (54.1)60 (16.7)260 (30.9)
  •  Laboratory work

4 (10.0)5 (12.5)1 (2.5)2 (5.0)7 (2.2)69 (19.2)88 (10.5)
  •  Meta-analysis

01 (2.5)5 (12.5)1 (2.5)15 (4.7)18 (5.0)40 (4.8)
  •  Other

1 (2.5)04 (10.0)1 (2.5)26 (8.1)26 (7.2)58 (6.9)
Sample size
  •  <30

4 (10.0)8 (20.0)7 (17.5)5 (12.5)34 (10.6)65 (18.1)120 (14.3)
  •  30–99

9 (22.5)9 (22.5)7 (17.5)9 (22.5)27 (8.4)62 (17.2)123 (14.6)
  •  100–300

12 (30.0)7 (17.5)9 (22.5)7 (17.5)39 (12.2)45 (12.5)117 (13.9)
  •  >300

15 (37.5)16 (40.0)17 (42.5)19 (47.5)206 (64.4)145 (40.3)423 (50.4)
  •  Missing

000014 (4.4)43 (11.9)57 (6.8)
Statistical significance of primary outcome
  •  Not significant

6 (15.0)4 (10.0)7 (17.5)5 (12.5)72 (22.5)41 (11.4)135 (16.1)
  •  Significant

30 (75.0)28 (70.0)21 (52.5)27 (67.5)162 (50.6)218 (60.6)486 (57.8)
  •  Not evaluated

4 (10.0)8 (20.0)12 (30.0)8 (20.0)86 (26.9)101 (28.0)219 (26.1)

Data are presented as number of articles (%), unless stated otherwise. AJRCCM: American Journal of Respiratory and Critical Care Medicine; ERJ: European Respiratory Journal; NEJM: New England Journal of Medicine.