TABLE 3

Differentially expressed genes in blood after azithromycin treatment involved in immune system processes

Gene symbolGene namep-valueFold changeRegulationProbeIDAccession
SYKSpleen tyrosine kinase0.0381.8down110685NM_003177.3
HLA-DRB3Major histocompatibility complex, class II, DR beta 30.0411.8down1770504NM_022555.3
GBP5Guanylate binding protein 50.0031.7down1510364NM_052942.2
FCGR1BFc fragment of IgG, high affinity Ib, receptor (CD64), transcript variant 10.0151.6down2710709NM_001017986.1
OAS22′-5′-oligoadenylate synthetase 2, 69/71 kDa, transcript variant 10.0391.6down7320561NM_016817.2
OAS12′,5′-oligoadenylate synthetase 1, 40/46 kDa, transcript variant 30.0041.6down1090390NM_001032409.1
IL4RInterleukin 4 receptor, transcript variant 10.0241.5down5910609NM_000418.2
GBP1Guanylate binding protein 1, interferon-inducible, 67 kDa0.0241.5down2190148NM_002053.1
GBP2Guanylate binding protein 2, interferon-inducible0.0031.5down1940162NM_004120.3
TAP1Transporter 1, ATP-binding cassette, sub-family B0.0201.4down7330392NM_000593.5
FYNFYN oncogene related to SRC, FGR, YES, transcript variant 20.0391.4down4860050NM_153047.1
OASL2′-5′-oligoadenylate synthetase-like, transcript variant 20.0441.4down7650097NM_198213.1
IL1RNInterleukin 1 receptor antagonist, transcript variant 10.0361.4down2470601NM_173842.1
IFI16Interferon, gamma-inducible protein 160.0211.4down3870594NM_005531.1
FCGR1AFc fragment of IgG, high affinity Ia, receptor (CD64)0.0381.4down520086NM_000566.2
HLA-HMajor histocompatibility complex, class I, H (pseudogene), non-coding RNA.0.0451.4down5870521NR_001434.1
LILRB2Leukocyte immunoglobulin-like receptor, subfamily B, member 2, transcript variant 20.0171.4down540671NM_001080978.1
PTPRCProtein tyrosine phosphatase, receptor type, C, transcript variant 40.0201.3down6180288NM_080923.2
IRF7Interferon regulatory factor 7, transcript variant b0.0041.3down1470382NM_004029.2
IL7RInterleukin 7 receptor0.0401.3down3830349NM_002185.2
IGSF6Immunoglobulin superfamily, member 60.0411.3down3850202NM_005849.1
ILF2Interleukin enhancer binding factor 2, 45 kDa0.0381.3down5690437NM_004515.2
OAS12′,5′-oligoadenylate synthetase 1, 40/46 kDa, transcript variant 30.0471.3down7040035NM_001032409.1
HLA-FMajor histocompatibility complex, class I, F0.0351.3down7330053NM_018950.1
PTPRCProtein tyrosine phosphatase, receptor type, C, transcript variant 20.0181.4down2600408NM_080921.2
HLA-GHLA-G histocompatibility antigen, class I, G0.0441.3down2070088NM_002127.3
BNIP3LBCL2/adenovirus E1B 19 kDa interacting protein 3-like0.0321.4up2640192NM_004331.2