Subjects | 22 | 22 | |
Demographics | | | |
Age years | 70±9 | 75±6 | 0.04* |
Sex | | | 0.53 |
Male | 13 (59) | 15 (68) | |
Female | 9 (41) | 7 (32) | |
Active smoker | 10 (45) | 5 (23) | 0.20 |
Ex-smoker | 12 (55) | 17 (77) | |
Smoking history pack-years | 39 (24–59) | 45 (28–93) | 0.41 |
Exacerbation within last year | 1 (0–2) | 0 (0–1) | 0.21 |
Hospitalisation due to exacerbations within last year | 0 (0–1) | 0 (0–0) | 0.03* |
Medications | | | |
SABA | 15 (68) | 15 (68) | 0.81 |
LABA | 15 (68) | 9 (41) | 0.09 |
SAMA | 0 | 0 | |
LAMA | 16 (73) | 8 (36) | 0.02* |
ICS | 12 (54) | 7 (32) | 0.16 |
Nonrespiratory medications | 17 (77) | 20 (91) | 0.09 |
Diabetes | 0 | 0 | |
Pulmonary function | | | |
FEV1 L | 1.2 (1–2) | 1.6 (1–2) | 0.27 |
FEV1 % pred | 52±19 | 59±22 | 0.18 |
FEV1/FVC % | 54±12 | 53±13 | 0.90 |
Anthropometric measurements | | | |
Weight kg | 68±13 | 75±16 | 0.12 |
Waist circumference cm | 92±14 | 96±15 | 0.46 |
Hip circumference cm | 98±9 | 104±11 | 0.04* |
Mid-thigh circumference cm | 56±8 | 59±6 | 0.16 |
Body composition | | | |
Fat mass kg | 24±7 | 26±6 | 0.50 |
BMI kg·m−2 | 23±4 | 24±4 | 0.36 |
Fat-free mass kg | 43±10 | 49±13 | 0.12 |
FFMI kg·m−2 | 15±3 | 16±3 | 0.17 |
Functional outcomes | | | |
ISWT m | 265±133 | 269±130 | 0.92 |
mMRC grade | 3 (2–3) | 3 (2–3) | 0.87 |
Right handgrip kg | 26±19 | 30±10 | 0.15 |
Left handgrip kg | 25±9 | 29±9 | 0.16 |
STS5 s | 11 (7–13) | 10 (9–12) | 0.94 |
Questionnaires | | | |
CAT score | 20±8 | 18±6 | 0.37 |
Anxiety (HADS) score | 6 (4–9) | 4 (3–10) | 0.42 |
Depression (HADS) score | 6±3 | 5±3 | 0.19 |
SGRQ total score | 52±17 | 41±13 | 0.02* |
SGRQ symptoms score | 63±23 | 52±21 | 0.14 |
SGRQ activity score | 57 (57–86) | 57 (53–69) | 0.03* |
SGRQ impact score | 38±19 | 27±12 | 0.03* |
MUST score | 0 (0–1) | 0 (0–0) | 0.50 |
Physical activity steps·day−1 | 2663 (1947–4912) | 4297 (1726–7211) | 0.33 |