Subjects n | 2482 | 10 245 |
Blood eosinophil count per 100-cells·µL−1 increase | 0.26 (0.12–0.56) | <0.001 | 0.78 (0.63–0.96) | 0.020 |
Male | 1.53 (1.19–1.98) | 0.001 | 1.15 (1.03–1.29) | 0.016 |
Age per 10 years | | | 1.24 (1.17–1.32) | <0.001 |
Underweight, BMI <18.5 kg·m−2 | 2.29 (1.53–3.43) | <0.001 | 1.41 (1.17–1.70) | <0.001 |
Smoking habits |
Current smoker | 1.74 (1.04–2.91) | 0.034 | | |
Ex-smoker | 1.66 (1.02–2.71) | 0.042 | | |
Cardiovascular disease | 2.18 (1.61–2.95) | <0.001 | | |
COPD exacerbations per 1 increase | 1.12 (1.07–1.17) | <0.001 | 1.09 (1.06–1.12) | <0.001 |
mMRC dyspnoea scale score |
Maximum score | 1.69 (1.05–2.70) | 0.030 | 1.28 (1.06–1.55) | 0.012 |
Missing# | | | 1.25 (1.06–1.48) | 0.008 |
FEV1 % pred |
<30% | | | 1.36 (1.15–1.62) | <0.001 |
Missing# | | | 1.26 (1.09–1.45) | 0.008 |
Triple therapy¶ prescribed | | | 1.19 (1.05–1.34) | 0.005 |