Subjects n | 96 | 107 | | |
Male | 63 (66) | 61 (57) | 124 | 0.21 |
Prematurity <35 WG | 16 (17) | 18 (17) | 34 | 0.98 |
Age years (mean±sd) | 2.24±2.12 | 5.53±4.13 | 203 | <0.001 |
<3 years | 72 (75) | 42 (39) | 114 | <0.001 |
3–6 years | 18 (19) | 26 (24) | 44 | 0.34 |
>6 years | 6 (6.2) | 39 (36) | 45 | <0.001 |
Age at onset months (mean±sd) | 6.15±8.98 | 12.5±21.6 | 200 | <0.01 |
Atopy | | | | |
Patient# | 34 (47) | 83 (84) | 117 | <0.001 |
Family# | 70 (80) | 90 (87) | 160 | 0.14 |
Passive smoking# | 29 (35) | 37 (35) | 66 | 0.99 |
Hospitalisation# | 79 (84) | 72 (68) | 151 | <0.01 |
Hospitalisation (mean±sd) | 2.42±1.41 | 2.86±1.87 | 151 | 0.11 |
ICU hospitalisation# | 22 (24) | 16 (15) | 38 | 0.12 |
Current asthma symptoms | 29 (30) | 4 (3.7) | 33 | <0.001 |
High-dose inhaled corticosteroids associated with another controller therapy# | 24 (25) | 70 (68) | 94 | <0.001 |
Uncontrolled or partially controlled asthma | 72 (75) | 85 (79) | 157 | 0.45 |
Systematised alveolar opacities on chest radiography# | 7 (8.1) | 5 (5.4) | 12 | 0.46 |
Elevated eosinophils >500 per mm3# | 9 (13) | 19 (19) | 28 | 0.27 |
Lung function tests | 3 (3.1) | 36 (33.6) | 39 | <0.001 |
Normal | 3 (100) | 26 (72) | 29 | 0.56 |