Chest
Clinical InvestigationsSLEEPDaytime Sleepiness and EEG Spectral Analysis in Apneic Patients Before and After Treatment With Continuous Positive Airway Pressure
Section snippets
Subjects
Fourteen subjects (13 men and 1 woman; age range, 34 to 58years; mean age [± SD], 45.0 ± 6.4 years) withmoderate-to-severe OSAS were studied before and after 6 to 9 months oftreatment with CPAP. Inclusion criteria were the presence of anapnea-hypopnea index (AHI) > 10 events per hour of sleep and aminimum arterial oxygen saturation(Sao2) level < 80%. Tenhealthy subjects (nine men and one woman; age range, 36 to 55 years; mean age, 44.2 ± 6.1 years) served as a control group. The healthysubjects
Respiratory and Polysomnographic Variables
Untreated OSAS patients were statistically different from controlsubjects for body mass index (BMI) and all sleep-related respiratoryvariables (ie, minimal, Sao2 value, time spent at< 90% of oxygen saturation, and AHI) (Table 1).
Between-group differences also were found for polysomnographicvariables (Table 2). Apneic patients hadlower percentages of slow-wave sleep and REM sleep and had lower REMsleep efficiency (ie, time spent in REM sleep over theentire duration of the REM sleep period). They
Discussion
To our knowledge, this is the first time that q, EEGs have beenperformed during REM sleep and wakefulness in OSAS patients before andafter treatment with CPAP.
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Cited by (102)
Sleepiness, continuous positive airway pressure and the obstructive sleep apnea hypopnea syndrome
2018, Revue des Maladies RespiratoiresQuantitative electroencephalogram measures in adult obstructive sleep apnea – Potential biomarkers of neurobehavioural functioning
2017, Sleep Medicine ReviewsCitation Excerpt :In general, when topographical distributions of brain activity are assessed, EEG abnormalities during wake occur in frontal and central brain regions [34,36–40]. The majority of the sleep qEEG studies used a single EEG derivation for PSA, but in three studies using multiple electrode sites (including 256-channel high density EEG), sleep EEG abnormalities were present across multiple brain regions including the frontal, central and parietal lobes [34,40,60]. High density EEG acquisitions allow for more detailed observations of the local, use-dependent changes of sleep EEG rhythms [93].
Evaluation of wakefulness electroencephalogram in OSA patients
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