Problem: To provide an evidence-based definition for the relationship between three subjective instruments for assessing severity of chronic rhinosinusitis- visual analogue scale, 'mild' 'moderate' and 'severe' (MMS) classification and perception of whether quality of life (QoL) is affected.
Method of study: One hundred sixteen subjects with chronic rhinosinusitis filled in a questionnaire rating simultaneously their perception of disease severity based (1) upon visual analogue scale, (2) MMS classification and (3) stating whether they felt their QoL was affected.
Main results: The mean age of subjects was 50. The inter-quartile range of VAS scores for the respective MMS groups were: Mild 0.80-3.50, Moderate 4.40-6.33, Severe 7.70-9.50. In the group who perceived effects on QoL, the inter-quartile range for VAS scores was 5.10-8.68. This range was 1.53-4.57 in the other group with no effects on QoL. 30.3% of patients in the 'mild' category, 79.6% in the 'moderate' category and 97.4% in the 'severe' category felt that their QoL was affected.
Principle conclusions: We propose a statistically validated definition of the relationship between MMS classification and VAS scoring. Based on our study we would define 'mild' as being 0- 3 inclusive, 'moderate, as > 3- 7 inclusive and 'severe' as > 7- 10 inclusive on the VAS scoring system. We further propose that in general QoL is more likely to be affected with VAS scores of 5 or more.