Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations
A Papi, CM Bellettato, F Braccioni… - American journal of …, 2006 - atsjournals.org
Rationale: Severe exacerbations of chronic obstructive pulmonary disease (COPD) are
major causes of health care costs mostly related to hospitalization. The role of infections in …
major causes of health care costs mostly related to hospitalization. The role of infections in …
Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019
…, F Martinez, MM de Oca, A Papi… - European …, 2019 - Eur Respiratory Soc
Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …
and biological information in order to optimise the therapeutic benefit relative to the …
Management of COPD exacerbations: a European respiratory society/American thoracic society guideline
…, RK Albert, A Anzueto, GJ Criner, A Papi… - European …, 2017 - Eur Respiratory Soc
This document provides clinical recommendations for treatment of chronic obstructive
pulmonary disease (COPD) exacerbations. Comprehensive evidence syntheses, including meta-…
pulmonary disease (COPD) exacerbations. Comprehensive evidence syntheses, including meta-…
European Respiratory Society guidelines for the diagnosis of asthma in adults
…, M Thomas, M Idzko, A Papi… - European …, 2022 - Eur Respiratory Soc
Although asthma is very common, affecting 5–10% of the population, the diagnosis of
asthma in adults remains a challenge in the real world, which results in both over- and under-…
asthma in adults remains a challenge in the real world, which results in both over- and under-…
Global initiative for the diagnosis, management, and prevention of chronic obstructive lung disease. The 2020 GOLD science committee report on COVID-19 and …
DMG Halpin, GJ Criner, A Papi, D Singh… - American journal of …, 2021 - atsjournals.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has raised
many questions about the management of patients with chronic obstructive pulmonary …
many questions about the management of patients with chronic obstructive pulmonary …
An official American Thoracic Society/European Respiratory Society statement: research questions in chronic obstructive pulmonary disease
…, M Miravitlles, PM Meek, A Papi… - American journal of …, 2015 - atsjournals.org
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity,
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…
Respiratory syncytial virus prefusion F protein vaccine in older adults
A Papi, MG Ison, JM Langley, DG Lee… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is an important cause of acute respiratory
infection, lower respiratory tract disease, clinical complications, and death in older adults. There …
infection, lower respiratory tract disease, clinical complications, and death in older adults. There …
Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a …
ER Bleecker, JM FitzGerald, P Chanez, A Papi… - The Lancet, 2016 - thelancet.com
Background Eosinophilia is associated with worsening asthma severity and decreased lung
function, with increased exacerbation frequency. We assessed the safety and efficacy of …
function, with increased exacerbation frequency. We assessed the safety and efficacy of …
Role of deficient type III interferon-λ production in asthma exacerbations
…, ST Holgate, DE Davies, SV Kotenko, A Papi… - Nature medicine, 2006 - nature.com
Rhinoviruses are the major cause of asthma exacerbations, and asthmatics have increased
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …
Dupilumab for COPD with type 2 inflammation indicated by eosinophil counts
…, M Bafadhel, SA Christenson, A Papi… - … England Journal of …, 2023 - Mass Medical Soc
Background In some patients with chronic obstructive pulmonary disease (COPD), type 2
inflammation may increase exacerbation risk and may be indicated by elevated blood …
inflammation may increase exacerbation risk and may be indicated by elevated blood …