The emergence of drug-resistant strains of Mycobacterium tuberculosis is a challenge to
global tuberculosis (TB) control. Although culture-based methods have been regarded as the …

The emergence of multidrug-resistant tuberculosis (MDR-TB; defined as resistance to at least
rifampicin and isoniazid) represents a growing threat to public health and economic growth…

Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-based
methods being considered the gold standard for drug susceptibility testing, molecular …

Objectives We examined the data reported in studies for diagnostic purposes and to discuss
whether their intended use could be extended to triage, as rule-in or rule-out tests to select …

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) is an emerging
threat to TB control in Ukraine, a country with the third highest XDR TB burden globally. …

Tuberculosis (TB) diagnosis is increasingly based on the detection of Mycobacterium
tuberculosis complex (MTBC) DNA in sputum using molecular diagnostic tests as the first test for …

Objectives To determine the sensitivity and specificity of AID TB Resistance line probe assay
(AID Diagnostika, Germany) to detect Mycobacterium tuberculosis and its resistance to first- …

Current diagnostics for tuberculosis (TB) only manage to confirm a small proportion of children
with TB and require respiratory samples, which are difficult to obtain. There is a need for …

The measurement of specific T-cell responses can be a useful tool for COVID-19 diagnostics
and clinical management. In this study, we evaluated the IFN-γ T-cell response against the …

Objective To study the diagnostic accuracy of a multiplex real-time PCR (Anyplex II MTB/MDR/XDR,
Seegene, Corea) that detects Mycobacterium tuberculosis resistant to isoniazid (INH)…