Background COPD exacerbations accelerate disease progression. Aims To examine if
COPD characteristics and systemic inflammatory markers predict the risk for acute COPD …

… Author contributions: GR Husebø, JA Hardie, PS Bakke and TM Eagan designed the study.
… GR Husebø and TM Eagan analysed the data and drafted the manuscript. All authors have …

… exerts opposing effects under conditions of low-grade and high-grade thrombin generation.
Under conditions of low-grade thrombin generation, thrombin binds to thrombomodulin to …

Background The fungal part of the pulmonary microbiome (mycobiome) is understudied. We
report the composition of the oral and pulmonary mycobiome in participants with COPD …

Background COPD patients have an increased risk of developing lung cancer, but the underlying
mechanisms are poorly understood. We aimed to identify risk factors for lung cancer in …

The aim was to evaluate susceptibility of oropharyngeal contamination with various
bronchoscopic sampling techniques. 67 patients with obstructive lung disease and 58 control …

Aim The aim of this study was to investigate whether the compositionality of the lower
airway microbiota predicts later exacerbation risk in persons with COPD in a cohort study. …

Macrophage migration inhibitor factor (MIF) is a pluripotent cytokine associated with several
different inflammatory conditions, but its role within lung inflammation and chronic …

Background Few studies have examined the stability of the pulmonary mycobiome. We
report longitudinal changes in the oral and pulmonary mycobiome of participants with and …

Background Data on discomfort and complications from research bronchoscopy in chronic
obstructive pulmonary disease (COPD) and asthma is limited. We present complications and …