The Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)
study was a large 3-year observational controlled multicentre international study aimed at …

The cytochrome p450 enzyme, CYP2D6, metabolises approximately 20% of marketed drugs.
CYP2D6 multiple variants are associated with altered enzyme activities. Genotyping 1018 …

This study examines the relationship between organizational commitment and supervisory
commitment (commitment to supervisor) in terms of their effects on employee outcomes in the …

1Health & Environmental Sciences, Dow Corning Corporation, Midland, Michigan 48686
2Covance Laboratories Inc., Vienna, Virginia 22182 3Pathco Inc., Frederick, Maryland 21702 …

The primary cilium is an antenna-like structure that protrudes from the cell surface of
quiescent/differentiated cells and participates in extracellular signal processing 1 , 2 , 3 . Here, we …

We have constructed the physical map of the 0.8 megabase DNA fragment which contains
the 3′ 64 variable region (V) gene segments of the human immunoglobulin heavy chain (H) …

… Dr Riley has reported to CHEST that no potential conflicts of interest exist with any
companies/organizations whose products or services may be discussed in this article. …

There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics
were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of …

Exercise tests are often used to evaluate the functional status of patients with COPD. However,
to the best of our knowledge, a comprehensive systematic comparison of these tests has …

Introduction Chronic obstructive pulmonary disease (COPD) is an increasingly common cause
of death worldwide. Its cardinal symptoms include breathlessness and severely reduced …