There is a need to re-evaluate the concept of asthma and chronic obstructive pulmonary
disease (COPD) as separate conditions, and to consider situations when they may coexist, or …

BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked heterogeneity,
but with a significant genetic contribution. Identifying exact causative genes has been …

OBJECTIVE: To update clinicians on the reproductive implications of premutations in FMR1 (fragile
X mental retardation 1). Fragile X syndrome, a cause of mental retardation and autism…

STUDY QUESTION Can a consensus and evidence-driven set of terms and definitions be
generated to be used globally in order to ensure consistency when reporting on infertility …

After 30 years, Obstetrics: Normal and Problem Pregnancies remains your go-to choice for
authoritative guidance on managing today’s obstetric patient. International experts put the …

Background Chromosomal microarray analysis has emerged as a primary diagnostic tool for
the evaluation of developmental delay and structural malformations in children. We aimed …

Objective: The authors sought to investigate the detection of non‐eosinophilic asthma using
induced sputum. Although this is an important subtype of clinical asthma, its recognition is …

Background Multiple early reports of patients admitted to hospital with COVID-19 showed
that patients with chronic respiratory disease were significantly under-represented in these …

Systematic genetic studies in endometriosis apparently have not been conducted; therefore,
we studied 123 patients with histologically proved endometriosis. Nine of 153 (5.8%) female …

Study objectives: To identify the characteristics of airway inflammation in persistent asthma
and to examine the role of neutrophilic inflammation in noneosinophilic persistent asthma. …