The Sleep Revolution project: the concept and objectives

…, D Pevernagie, R Sund, J Töyräs… - Journal of sleep …, 2022 - Wiley Online Library
Obstructive sleep apnea is linked to severe health consequences such as hypertension,
daytime sleepiness, and cardiovascular disease. Nearly a billion people are estimated to have …

[HTML][HTML] The influence of wearables on health care outcomes in chronic disease: systematic review

…, D Forrester, C Dobbins, D Smith, J Töyräs… - Journal of Medical …, 2022 - jmir.org
Background Chronic diseases contribute to high rates of disability and mortality. Patient
engagement in chronic disease self-management is an essential component of chronic disease …

Characterization of connective tissues using near-infrared spectroscopy and imaging

…, JK Sarin, S Kandel, N Pleshko, J Töyräs - Nature …, 2021 - nature.com
Near-infrared (NIR) spectroscopy is a powerful analytical method for rapid, non-destructive
and label-free assessment of biological materials. Compared to mid-infrared spectroscopy, …

Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation

…, MS Laasanen, J Töyräs, J Rieppo, J Hirvonen… - Journal of …, 2002 - Elsevier
At mechanical equilibrium, articular cartilage is usually characterized as an isotropic elastic
material with no interstitial fluid flow. In this study, the equilibrium properties (Young's …

T2 relaxation reveals spatial collagen architecture in articular cartilage: A comparative quantitative MRI and polarized light microscopic study

MT Nieminen, J Rieppo, J Töyräs… - … in Medicine: An …, 2001 - Wiley Online Library
It has been suggested that orientational changes in the collagen network of articular
cartilage account for the depthwise T 2 anisotropy of MRI through the magic angle effect. To …

Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage

RK Korhonen, MS Laasanen, J Töyräs… - Journal of …, 2003 - Elsevier
Degradation of collagen network and proteoglycan (PG) macromolecules are signs of articular
cartilage degeneration. These changes impair cartilage mechanical function. Effects of …

Biomechanical properties of knee articular cartilage

MS Laasanen, J Töyräs, RK Korhonen, J Rieppo… - …, 2003 - content.iospress.com
Abstract Structure and properties of knee articular cartilage are adapted to stresses
exposed on it during physiological activities. In this study, we describe site‐and depth‐dependence …

Quantitative MR microscopy of enzymatically degraded articular cartilage

MT Nieminen, J Töyräs, J Rieppo… - … in Medicine: An …, 2000 - Wiley Online Library
Structural changes in bovine patellar articular cartilage, induced by component selective
enzymatic treatments, were investigated by measuring tissue T 2 relaxation at 9.4 T. This MRI …

Collagen network primarily controls Poisson's ratio of bovine articular cartilage in compression

…, RK Korhonen, P Julkunen, J Töyräs… - Journal of …, 2006 - Wiley Online Library
The equilibrium Young's modulus of articular cartilage is known to be primarily determined
by proteoglycans (PGs). However, the relation between the Poisson's ratio and the …

Spatial assessment of articular cartilage proteoglycans with Gd‐DTPA‐enhanced T1 imaging

…, J Rieppo, J Silvennoinen, J Töyräs… - … in Medicine: An …, 2002 - Wiley Online Library
In Gd‐DTPA‐enhanced T 1 imaging of articular cartilage, the MRI contrast agent with two
negative charges is understood to accumulate in tissue inversely to the negative charge of …