Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up

Y Peker, J Hedner, J Norum, H Kraiczi… - American journal of …, 2002 - atsjournals.org
The incidence of a cardiovascular disease (CVD) was explored in a consecutive sleep clinic
cohort of 182 middle-aged men (mean age, 46.8 ± 9.3; range, 30–69 years in 1991) with or …

Augmented resting sympathetic activity in awake patients with obstructive sleep apnea

JT Carlson, J Hedner, M Elam, H Ejnell, J Sellgren… - Chest, 1993 - Elsevier
Muscle nerve sympathetic activity (MSA) was recorded during wakefulness in 11 patients
with obstructive sleep apnea (OSA) and in 9 sex- and age-matched healthy control subjects. …

Respiratory disturbance index: an independent predictor of mortality in coronary artery disease

Y Peker, JAN Hedner, H KRAICZI… - American journal of …, 2000 - atsjournals.org
Cardiovascular mortality was prospectively investigated in consecutive coronary artery
disease (CAD) patients with versus without obstructive sleep apnea (OSA) during a follow-up …

Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?

J Hedner, H Ejnell, J Sellgren, T Hedner… - Journal of …, 1988 - journals.lww.com
Muscle nerve sympathetic activity was recorded in six patients with the sleep apnoea
syndrome (SAS). Compared with age-and sex-matched control patients, an increased activity …

Therapeutic electrical stimulation of the hypoglossal nerve in obstructive sleep apnea

…, PL Smith, W De Backer, J Hedner… - … –Head & Neck …, 2001 - jamanetwork.com
Background Hypoglossal nerve stimulation has been demonstrated to relieve upper airway
obstruction acutely, but its effect on obstructive sleep apnea is not known. Objective To …

Attenuated endothelium-dependent vascular relaxation in patients with sleep apnoea

JT Carlson, C Rångemark, JA Hedner - Journal of hypertension, 1996 - journals.lww.com
Results Forearm blood flow after acetylcholine infusion was reduced in patients compared
with that in controls (peak flows were 6.0+/-0.7 and 9.8+/-1.5 ml/min for 100g, respectively), …

Impairment of vascular endothelial function and left ventricular filling: association with the severity of apnea-induced hypoxemia during sleep

H Kraiczi, K Caidahl, A Samuelsson, J Hedner - Chest, 2001 - Elsevier
Study objective To investigate whether a dose-effect relationship exists between the severity
of obstructive sleep apnea (OSA) and subclinical indicators of myocardial or vascular …

Left ventricular hypertrophy independent of hypertension in patients with obstructive sleep apnoea

J Hedner, H Ejnell, K Caidahl - Journal of hypertension, 1990 - journals.lww.com
To evaluate cardiac structure and function as well as blood pressure in the obstructive sleep
apnoea syndrome (OSAS), we investigated 61 male patients and 61 male controls with M-…

Depressed baroreflex sensitivity in patients with obstructive sleep apnea.

JT Carlson, JA Hedner, J Sellgren, M Elam… - American journal of …, 1996 - atsjournals.org
Muscle nerve sympathetic activity (MSA), the interval between two R-waves in the ECG, or
the interbeat interval (RR-interval), and blood pressure (BP) were recorded in 10 awake …

Recommendations for the management of patients with obstructive sleep apnoea and hypertension

G Parati, C Lombardi, J Hedner, MR Bonsignore… - 2013 - Eur Respiratory Soc
This article is aimed at addressing the current state-of-the-art in epidemiology, pathophysiology,
diagnostic procedures and treatment options for appropriate management of obstructive …