It is widely accepted that systemic neoplastic spread is a late event in tumour progression.
However, sometimes, rapidly invasive cancers are diagnosed because of appearance of …

The neurotrophic tropomyosin receptor kinase (NTRK) genes (NTRK1, NTRK2, and NTRK3)
code for three transmembrane high-affinity tyrosine-kinase receptors for nerve growth …

Caveolae are non‐clathrin invaginations of the plasma membrane in most cell types; they
are involved in signalling functions and molecule trafficking, thus modulating several …

Recent studies identified a poor-prognosis stem/serrated/mesenchymal (SSM) transcriptional
subtype of colorectal cancer (CRC). We noted that genes upregulated in this subtype are …

… To this end, we used the MergeMaid R-package to calculate a gene reproducibility index
called ICOR 65,66 , which allows to identify genes that are reproducible across distinct data …

Background Survival in mycosis fungoides ( MF ) is varied and may be poor. The PROCLIPI
( PRO spective Cutaneous Lymphoma International Prognostic Index) study is a web‐based …

Pure invasive micropapillary carcinoma (MPC) is a special histological type that accounts for
0.7–3% of all breast cancers. MPC has a distinctive growth pattern and a more aggressive …

Background Sentinel lymph node biopsy (SLNB) is currently recommended for patients with
intermediate-thickness melanomas (T2–T3). Historically, T4 melanoma patients have not …

Background Diagnosis and proper management of atypical Spitz tumors in pediatric age are
still controversial. Objective We sought to investigate the clinicopathological and molecular …

Background The prognostic significance of regression in primary melanoma has been debated
over the past few years. Once it was considered to be a negative prognostic factor, as it …