Accuracy of FENO for diagnosing asthma: a systematic review
S Karrasch, K Linde, G Rücker, H Sommer… - Thorax, 2017 - thorax.bmj.com
Background Measurement of FE NO might substitute bronchial provocation for diagnosing
asthma. We aimed to investigate the diagnostic accuracy of FE NO measurement compared …
asthma. We aimed to investigate the diagnostic accuracy of FE NO measurement compared …
[HTML][HTML] Aging and induced senescence as factors in the pathogenesis of lung emphysema
S Karrasch, O Holz, RA Jörres - Respiratory medicine, 2008 - Elsevier
Classically, the development of emphysema in chronic obstructive pulmonary disease is
believed to involve inflammation induced by cigarette smoke and leukocyte activation, including …
believed to involve inflammation induced by cigarette smoke and leukocyte activation, including …
Genome-wide association study identifies five loci associated with lung function
…, C Cooper, E Dennison, S Shaheen, S Karrasch… - Nature …, 2010 - nature.com
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
…, AL James, S Jankovic, BR Joubert, S Karrasch… - Nature …, 2011 - nature.com
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …
[HTML][HTML] COVID-19 and heat waves: New challenges for healthcare systems
Heat waves and Covid-19 overlap, as this pandemic continues into summer 2021. Using a
narrative review, we identified overlapping risk groups and propose coping strategies. The …
narrative review, we identified overlapping risk groups and propose coping strategies. The …
The 8.5 A projection map of the light‐harvesting complex I from Rhodospirillum rubrum reveals a ring composed of 16 subunits.
S Karrasch, PA Bullough, R Ghosh - The EMBO journal, 1995 - embopress.org
… The magnification was X35 000 and exposure time was 1.0 s with a beam of -2.5 gm diameter
at the specimen. This resulted in an electron doseof five to 10 electrons/A2. Images were …
at the specimen. This resulted in an electron doseof five to 10 electrons/A2. Images were …
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …
[HTML][HTML] Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary …
…, TM Bartz, SA Gharib, C Flexeder, S Karrasch… - Nature …, 2023 - nature.com
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung …
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung …
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
…, M Imboden, NM Probst-Hensch, S Karrasch… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association discovery …
and is the third leading cause of death globally. Through genome-wide association discovery …