Accuracy of FENO for diagnosing asthma: a systematic review

S Karrasch, K Linde, G Rücker, H Sommer… - Thorax, 2017 - thorax.bmj.com
Background Measurement of FE NO might substitute bronchial provocation for diagnosing
asthma. We aimed to investigate the diagnostic accuracy of FE NO measurement compared …

[HTML][HTML] Aging and induced senescence as factors in the pathogenesis of lung emphysema

S Karrasch, O Holz, RA Jörres - Respiratory medicine, 2008 - Elsevier
Classically, the development of emphysema in chronic obstructive pulmonary disease is
believed to involve inflammation induced by cigarette smoke and leukocyte activation, including …

Genome-wide association study identifies five loci associated with lung function

…, C Cooper, E Dennison, S Shaheen, S Karrasch… - Nature …, 2010 - nature.com
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

…, AL James, S Jankovic, BR Joubert, S Karrasch… - Nature …, 2011 - nature.com
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

…, NG Martin, DL Duffy, N Novak, H Schulz, S Karrasch… - Nature …, 2017 - nature.com
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …

[HTML][HTML] COVID-19 and heat waves: New challenges for healthcare systems

…, N Gerrett, MMTE Huynen, J Lee, S Karrasch… - Environmental …, 2021 - Elsevier
Heat waves and Covid-19 overlap, as this pandemic continues into summer 2021. Using a
narrative review, we identified overlapping risk groups and propose coping strategies. The …

The 8.5 A projection map of the light‐harvesting complex I from Rhodospirillum rubrum reveals a ring composed of 16 subunits.

S Karrasch, PA Bullough, R Ghosh - The EMBO journal, 1995 - embopress.org
… The magnification was X35 000 and exposure time was 1.0 s with a beam of -2.5 gm diameter
at the specimen. This resulted in an electron doseof five to 10 electrons/A2. Images were …

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

…, JP Cook, BB Sun, J Zhou, J Hui, S Karrasch… - Nature …, 2019 - nature.com
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …

[HTML][HTML] Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary …

…, TM Bartz, SA Gharib, C Flexeder, S Karrasch… - Nature …, 2023 - nature.com
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung …

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

…, M Imboden, NM Probst-Hensch, S Karrasch… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association discovery …