Pulmonary epithelioid haemangioendothelioma in 21 patients, including three with partial spontaneous regression

…, H Itoh, H Asamoto, T Izumi… - European …, 1998 - Eur Respiratory Soc
This investigation studied the general conditions and prognostic factors of pulmonary
epithelioid haemangioendothelioma (PEH), which is a rare disease. Twenty-one patients were …

Leukotriene B4: metabolism and signal transduction

T Yokomizo, T Izumi, T Shimizu - Archives of biochemistry and biophysics, 2001 - Elsevier
Leukotriene B 4 (LTB 4 ) is known as one of the most potent chemoattractants and activators
of leukocytes and is involved in inflammatory diseases. Enzymes involved in the …

Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage

T Izumi, LR Wiederhold, G Roy, R Roy, A Jaiswal… - Toxicology, 2003 - Elsevier
The DNA base excision repair (BER) is a ubiquitous mechanism for removing damage from
the genome induced by spontaneous chemical reaction, reactive oxygen species (ROS) and …

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

T Yokomizo, T Izumi, K Chang, Y Takuwa, T Shimizu - Nature, 1997 - nature.com
… The remaining cDNAs were randomly subcloned into a T-vector (Promega). Sixty-six
clones were sequenced, and their sequences were compared with those in the GenBank/EMBL/…

Dyspnea is a better predictor of 5-year survival than airway obstruction in patients with COPD

K Nishimura, T Izumi, M Tsukino, T Oga - Chest, 2002 - Elsevier
… An unpaired t test and χ 2 test were used to compare backgrounds between the subjects
who were successfully followed up and those who were not, and between the nonsurviving …

American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias

…, RB Hubbard, Y Inoue, T Izumi… - … of respiratory and …, 2002 - mayoclinic.elsevierpure.com
Despite the considerable progress in the classification of the idiopathic interstitial pneumonias
(IIPs), the lack of an international standard has resulted in variable and confusing …

A Second Leukotriene B4 Receptor, Blt2: A New Therapeutic Target in Inflammation and Immunological Disorders

T Yokomizo, K Kato, K Terawaki, T Izumi… - The Journal of …, 2000 - rupress.org
Leukotriene B 4 (LTB 4 ) is a potent chemoattractant and activator of both granulocytes and
macrophages. The actions of LTB 4 appear to be mediated by a specific G protein–coupled …

[HTML][HTML] Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans

T Izumi, S Osawa, A Obata, K Tobe, M Saito… - The Journal of …, 2000 - Elsevier
Isoflavones are contained in soybean or soy foods in two chemical forms, ie, aglycones and
glucosides. We investigated the difference in the absorption of soy isoflavone aglycones and …

Prognostic determinants of long-term survival in Japanese patients with cardiac sarcoidosis treated with prednisone

…, S Morimoto, S Hiramitsu, T Nakano, T Izumi… - The American journal of …, 2001 - Elsevier
… Dichotomous variables were assessed with chi-square analysis, and continuous variables
were compared with the Student’s t test between the 2 cohorts. Survival rates were estimated …

[HTML][HTML] A mutation in the insulin 2 gene induces diabetes with severe pancreatic β-cell dysfunction in the Mody mouse

…, D Lu, K Takata, A Koizumi, T Izumi - The Journal of …, 1999 - Am Soc Clin Investig
The mouse autosomal dominant mutation Mody develops hyperglycemia with notable
pancreatic β-cell dysfunction. This study demonstrates that one of the alleles of the gene for …