[HTML][HTML] Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

…, JC Brisset, S Galbán, CJ Galbán… - The Journal of …, 2012 - Am Soc Clin Investig
Pancreatic cancer is almost invariably associated with mutations in the KRAS gene, most
commonly KRAS G12D , that result in a dominant-active form of the KRAS GTPase. However, …

Computed tomography–based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression

CJ Galbán, MK Han, JL Boes, KA Chughtai… - Nature medicine, 2012 - nature.com
Chronic obstructive pulmonary disease (COPD) is increasingly being recognized as a highly
heterogeneous disorder, composed of varying pathobiology. Accurate detection of COPD …

Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease

…, D Curran-Everett, CJ Galbán… - American journal of …, 2016 - atsjournals.org
Rationale: The small conducting airways are the major site of airflow obstruction in chronic
obstructive pulmonary disease and may precede emphysema development. Objectives: We …

[HTML][HTML] Functional diffusion map as an early imaging biomarker for high-grade glioma: correlation with conventional radiologic response and overall survival

DA Hamstra, CJ Galbán, CR Meyer… - Journal of clinical …, 2008 - ncbi.nlm.nih.gov
Purpose Assessment of radiologic response (RR) for brain tumors utilizes the Macdonald
criteria 8 to 10 weeks from the start of treatment. Diffusion magnetic resonance imaging (MRI) …

Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting

AJ Cole, AE David, J Wang, CJ Galbán, HL Hill… - Biomaterials, 2011 - Elsevier
While successful magnetic tumor targeting of iron oxide nanoparticles has been achieved in
a number of models, the rapid blood clearance of magnetically suitable particles by the …

Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles

AJ Cole, AE David, J Wang, CJ Galbán, VC Yang - Biomaterials, 2011 - Elsevier
Magnetic iron oxide nanoparticles (MNPs) have been studied to circumvent the limitations of
status-quo brain tumor therapy and can be targeted by applying an external magnetic field …

[HTML][HTML] Parametric response map as an imaging biomarker to distinguish progression from pseudoprogression in high-grade glioma

C Tsien, CJ Galbán, TL Chenevert… - Journal of Clinical …, 2010 - ncbi.nlm.nih.gov
Galbán, Thomas L. Chenevert, Alnawaz Rehemtulla, Brian D. Ross … Galbán, Thomas L.
Chenevert, Daniel A. Hamstra, Pia C. … Galbán CJ, Chenevert TL, Meyer CR. The parametric …

The parametric response map is an imaging biomarker for early cancer treatment outcome

CJ Galbán, TL Chenevert, CR Meyer, C Tsien… - Nature medicine, 2009 - nature.com
Here we describe the parametric response map (PRM), a voxel-wise approach for image
analysis and quantification of hemodynamic alterations during treatment for 44 patients with …

[HTML][HTML] Metastatic pancreatic cancer is dependent on oncogenic Kras in mice

…, F Bednar, J Pierre, KA Heist, CJ Galbán, S Galbán… - PloS one, 2012 - journals.plos.org
Pancreatic cancer is one of the deadliest human malignancies, and its prognosis has not
improved over the past 40 years. Mouse models that spontaneously develop pancreatic …

Multi‐system repeatability and reproducibility of apparent diffusion coefficient measurement using an ice‐water phantom

D Malyarenko, CJ Galbán, FJ Londy… - Journal of Magnetic …, 2013 - Wiley Online Library
Purpose: To determine quantitative quality control procedures to evaluate technical variability
in multi‐center measurements of the diffusion coefficient of water as a prerequisite to use …