Hydrogen cyanide, a volatile biomarker of Pseudomonas aeruginosa infection

D Smith, P Španěl, FJ Gilchrist… - Journal of breath …, 2013 - iopscience.iop.org
Since we first recognized the regular presence of gaseous hydrogen cyanide, HCN, in the
headspace of plate cultures of the bacterium Pseudomonas aeruginosa, PA, derived from …

Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic

…, R Harwood, DB Hawcutt, FJ Gilchrist… - The Lancet …, 2020 - thelancet.com
The eradication of poverty and hunger are the top sustainable development goals, adopted
by UN Member States in 2015. Yet the World Food Programme estimates that, in the wake of …

Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and without Pseudomonas aeruginosa infection

FJ Gilchrist, RJ Bright-Thomas, AM Jones… - Journal of breath …, 2013 - iopscience.iop.org
Elevated concentrations of hydrogen cyanide (HCN) have been detected in the headspace
of Pseudomonas aeruginosa (PA) cultures and in the breath of children with cystic fibrosis (…

The effect of long‐term untreated growth hormone deficiency (GHD) and 9 years of GH replacement on the quality of life (QoL) of GH‐deficient adults

FJ Gilchrist, RD Murray, SM Shalet - Clinical endocrinology, 2002 - Wiley Online Library
background Quality of life (QoL) is reduced in GH‐deficient adults compared with the normal
population. Further support for the role of GH in the maintenance of QoL is derived from …

Bronchoalveolar lavage in children with cystic fibrosis: how many lobes should be sampled?

FJ Gilchrist, S Salamat, S Clayton, J Peach… - Archives of disease in …, 2011 - adc.bmj.com
Background The European Respiratory Society guidance on bronchoalveolar lavage (BAL)
in children was published in 2000. It recommended taking one BAL specimen from the most …

[HTML][HTML] Bacterial distribution in the lungs of children with protracted bacterial bronchitis

…, M Samuels, J Alexander, W Lenney, FJ Gilchrist - PLoS …, 2014 - journals.plos.org
Objectives Flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is increasingly used
for the microbiological confirmation of protracted bacterial bronchitis (PBB) in children with …

Variation in hydrogen cyanide production between different strains of Pseudomonas aeruginosa

FJ Gilchrist, A Alcock, J Belcher, M Brady… - European …, 2011 - Eur Respiratory Soc
There is increasing interest in using the cyanogenic properties of Pseudomonas aeruginosa
to develop a nonmicrobiological method for its detection. Prior to this, the variation in …

[HTML][HTML] Exhaled breath hydrogen cyanide as a marker of early Pseudomonas aeruginosa infection in children with cystic fibrosis

FJ Gilchrist, J Belcher, AM Jones, D Smith… - ERJ open …, 2015 - Eur Respiratory Soc
Hydrogen cyanide is readily detected in the headspace above Pseudomonas aeruginosa
cultures and in the breath of cystic fibrosis (CF) patients with chronic (P. aeruginosa) infection. …

[HTML][HTML] Successful treatment of cepacia syndrome with a combination of intravenous cyclosporin, antibiotics and oral corticosteroids

FJ Gilchrist, AK Webb, RJ Bright-Thomas… - Journal of Cystic …, 2012 - Elsevier
Burkholderia cepacia complex (BCC) is a group of 17 closely related bacterial species that
can cause pulmonary infection in patients with cystic fibrosis (CF). The clinical manifestations …

Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis

J Green, FJ Gilchrist, W Carroll - Cochrane Database of …, 2018 - cochranelibrary.com
Background Cystic fibrosis (CF) is the most common, life‐limiting, genetically inherited
disease. It affects multiple organs, particularly the respiratory system. However, gastrointestinal …