It has been demonstrated that heart rate variability (HRV) is predictive of all-cause and
cardiovascular mortality using clinical ECG recordings. This is true for rest, exercise and …

Existing normal standards for maximal oxygen uptake (VO 2 max) are problematic because
they tend to be population specific, lack normal distribution and portability, and are poorly …

Borg’s rating of perceived exertion (RPE) is a widely used psycho-physical tool to assess
subjective perception of effort during exercise. We evaluated the association between Borg’s …

Genetic Diagnoses in Critical Care Because a genetic diagnosis can guide clinical management
and improve prognosis in critically ill patients, much effort has gone into developing …

The ability to measure physical activity through wrist-worn devices provides an opportunity for
cardiovascular medicine. However, the accuracy of commercial devices is largely unknown…

Background: Small studies have suggested that high-intensity interval training (HIIT) is superior
to moderate continuous training (MCT) in reversing cardiac remodeling and increasing …

Precision health relies on the ability to assess disease risk at an individual level, detect early
preclinical conditions and initiate preventive strategies. Recent technological advances in …

Importance Endurance exercise is effective in improving peak oxygen consumption (peak
V̇o 2 ) in patients with heart failure with preserved ejection fraction (HFpEF). However, it …

Acute physical activity leads to several changes in metabolic, cardiovascular, and immune
pathways. Although studies have examined selected changes in these pathways, the system-…

Whole-genome sequencing (WGS) can identify variants that cause genetic disease, but the
time required for sequencing and analysis has been a barrier to its use in acutely ill patients. …