α1-antitrypsin combines with plasma fatty acids and induces angiopoietin-like protein 4 expression
E Frenzel, S Wrenger, B Brügger, S Salipalli… - The Journal of …, 2015 - journals.aai.org
… Angptl4 is therefore a multifunctional protein, and there is a considerable interest in identifying
the regulators of Angptl4 … Zemaira is also termed A1AT-0 to indicate that it is FA free. …
the regulators of Angptl4 … Zemaira is also termed A1AT-0 to indicate that it is FA free. …
[HTML][HTML] Recent advances in live cell imaging of hepatoma cells
S Salipalli, PK Singh, J Borlak - BMC Cell Biology, 2014 - Springer
… of bioluminescent markers is not only limited to in vitro assays or live cell imaging but is also
… Efficient gene delivery in mammalian cells is another aspect of our review with appropriate …
… Efficient gene delivery in mammalian cells is another aspect of our review with appropriate …
[HTML][HTML] Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression
A Karadagi, H Johansson, H Zemack, S Salipalli… - PloS one, 2017 - journals.plos.org
The main goal of the therapy with purified human plasma alpha1-antitrypsin (A1AT) is to
increase A1AT levels and to prevent lungs from elastolytic activity in patients with PiZZ (Glu 342 …
increase A1AT levels and to prevent lungs from elastolytic activity in patients with PiZZ (Glu 342 …
Why do some adults with PiMZ α1-antitrypsin develop bronchiectasis?
N Aggarwal, BM Delgado, S Salipalli… - ERJ Open …, 2016 - Eur Respiratory Soc
… While Pseudomonas aeruginosa is recognised as the major pathogen, which is clearly
associated with adverse outcomes [15], the relevance of chronic airway infection by S. aureus …
associated with adverse outcomes [15], the relevance of chronic airway infection by S. aureus …
Alpha1-antitrypsin inhibits the ATP-induced release of monocytic interleukin-1β independent of its antiprotease activity
A Agné, K Siebers, S Wilker, S Salipalli, K Richter… - …, 2018 - thieme-connect.com
Materials and Methods: Native AAT from the plasma of healthy persons and from CPBS
patients was purified by affinity chromatography. Protein oxidation was performed with n-…
patients was purified by affinity chromatography. Protein oxidation was performed with n-…
Young adult with inherited PiMZ alpha-1-antitrypsin deficiency (A1ATD)-related bronchiectasis: characteristic of blood neutrophils and A1AT protein
N Aggarwal, BM Delgado, S Salipalli, N Matamala… - 2016 - Eur Respiratory Soc
… Whether there is an increased risk for bronchiectasis in heterozygous PiMZ A1ATD carriers
is not clear. We describe a non-smoking 18 years old male with bronchiectasis. Pulmonary …
is not clear. We describe a non-smoking 18 years old male with bronchiectasis. Pulmonary …
Why do some adults with PiMZ alpha1-antitrypin develop bronchiectasis?
N Aggarwal, BMD Delgado, S Salipalli… - …, 2016 - thieme-connect.com
Several reports indicate an association among inherited alpha-1-antitrypsin deficiency (A1ATD),
pulmonary infections and bronchiectasis. Most reported A1ATD cases with …
pulmonary infections and bronchiectasis. Most reported A1ATD cases with …
Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity
S Austermeier, M Pekmezović, P Porschitz, S Lee… - MBio, 2021 - Am Soc Microbiol
Albumin is abundant in serum but is also excreted at mucosal surfaces and enters tissues
when inflammation increases vascular permeability. Host-associated opportunistic pathogens …
when inflammation increases vascular permeability. Host-associated opportunistic pathogens …
The protease inhibitor cystatin C down-regulates the release of IL-β and TNF-α in lipopolysaccharide activated monocytes
ST Gren, S Janciauskiene, S Sandeep… - Journal of Leucocyte …, 2016 - academic.oup.com
Human cystatin C, a member of the cysteine proteinase-inhibitory family, is produced by all
nucleated cells and has important roles in regulating natural immunity. Nematode homologs …
nucleated cells and has important roles in regulating natural immunity. Nematode homologs …
[HTML][HTML] Vitamin D (1, 25 (OH) 2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1, 25 (OH) 2D3-driven IL-10
… Although this is a relatively moderate affinity binding interaction, it is plausible that it is
physiologically relevant given the high circulating levels of α-1-antitrypsin of around 20–48 μM [19]…
physiologically relevant given the high circulating levels of α-1-antitrypsin of around 20–48 μM [19]…