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Lung proteome and metabolome endotype in HIV-associated obstructive lung disease
BALF protein profile distinguishes HIV-associated obstructive lung disease. A unique endotype in black men with more severe obstructive lung disease was found that associated with signal transduction pathways, cell cycle and apoptosis.
Molecular assessment of mycobacterial burden in the treatment of nontuberculous mycobacterial disease
Molecular assays have been developed that are capable of quantifying NTM DNA in sputum. The assays were applied to 410 samples obtained from a cohort including patients on NTM treatment. The assays provide a fast and accurate measure of molecular burden.
Highlights from the Respiratory Failure and Mechanical Ventilation 2022 Conference
ERS Assembly 2 gathered in Berlin to organise the second Respiratory Failure and Mechanical Ventilation Conference in June 2022. A conference summary is presented here.
Impact of computed tomographic patterns and extent on clinical management and outcomes of patients with organising pneumonia
Patients with organising pneumonia whose CT images exhibit multilobe involvement and mixed patterns have an increased risk of adverse outcomes
All-cause admissions following a first ever exacerbation-related hospitalisation in COPD
Nonrespiratory events are the predominant cause of hospital admission in patients with COPD following their first ever exacerbation-related hospitalisation. These findings challenge the current global post-exacerbation management goals.

Latest Articles

Airway clearance treatments in bronchiectasis: feasibility of linking survey results to registry data and a survey of patients’ and physiotherapists’ practices
Rebecca H. McLeese, Katherine O'Neill, Brenda O'Neill, James D. Chalmers, Jeanette Boyd, Anthony De Soyza, Ryan McChrystal, Megan L. Crichton, Judy M. Bradley

ERJ Open Research Mar 2023, 9 (2) 00540-2022; DOI: 10.1183/23120541.00540-2022
Lung proteome and metabolome endotype in HIV-associated obstructive lung disease
Sarah Samorodnitsky, Eric F. Lock, Monica Kruk, Alison Morris, Janice M. Leung, Ken M. Kunisaki, Timothy J. Griffin, Chris H. Wendt

ERJ Open Research Mar 2023, 9 (2) 00332-2022; DOI: 10.1183/23120541.00332-2022
Highlights from the Respiratory Failure and Mechanical Ventilation 2022 Conference
Pedro Viegas, Elisa Ageno, Gabriele Corsi, Federico Tagariello, Léa Razakamanantsoa, Rudolfs Vilde, Carla Ribeiro, Leo Heunks, Maxime Patout, Christoph Fisser

ERJ Open Research Mar 2023, 9 (2) 00467-2022; DOI: 10.1183/23120541.00467-2022
Distribution of type 2 biomarkers and association with severity, clinical characteristics and comorbidities in the BREATHE real-life asthma population
Laurits Frøssing, Ditte K. Klein, Morten Hvidtfeldt, Nicolai Obling, Gunilla Telg, Jonas S. Erjefält, Uffe Bodtger, Celeste Porsbjerg

ERJ Open Research Mar 2023, 9 (2) 00483-2022; DOI: 10.1183/23120541.00483-2022
The impact of anti-eosinophilic therapy on exercise capacity and inspiratory muscle strength in patients with severe asthma
Elisa Franceschi, Nora Drick, Jan Fuge, Pierachille Santus, Bettina Fischer, Moritz Kayser, Tobias Welte, Hendrik Suhling

ERJ Open Research Mar 2023, 9 (2) 00341-2022; DOI: 10.1183/23120541.00341-2022
Molecular assessment of mycobacterial burden in the treatment of nontuberculous mycobacterial disease
Huw C. Ellis, Miriam F. Moffatt, Colin Churchward, Leah Cuthbertson, William O.C. Cookson, Michael R. Loebinger

ERJ Open Research Mar 2023, 9 (2) 00435-2022; DOI: 10.1183/23120541.00435-2022