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  • Exhaled volatile organic compounds associated with risk factors for obstructive pulmonary diseases: a systematic review
    Several risk factors for obstructive pulmonary diseases, including smoking, diet and BMI, may affect volatile organic compound (VOC) profiles. VOCs linked to risk (confounding) factors should be carefully considered when interpreting exhaled breath profil
  • Patients’ acceptance of outcome and experience measurements during hospitalisation for COPD exacerbations: a CICERO Clinical Research Collaboration–European Lung Foundation online patient survey
    In the CICERO–ELF patient survey, European patients endorsed a selection of outcome and experience measurements from a previously obtained expert consensus list, for standardised assessments during hospitalisation and follow-up of acute COPD exacerbations
  • Effects of pH alteration on respiratory syncytial virus in human airway epithelial cells
    Low airway surface pH impairs antimicrobial host defence and worsens airway inflammation. A novel, inhaled, alkaline buffer medication, Optate, raises airway pH and inhibits RSV infection in primary human airway epithelial cells in a dose-dependent manner
  • Endobronchial optical coherence tomography or computed tomography for evaluating progression of bronchiectasis
    Endobronchial optical coherence tomography imaging could reveal the evolution of thickened-walled bronchioles surrounding the dilated bronchi, indicating radiological progression of bronchiectasis
  • Lung microhaemorrhage drives oxidative/inflammatory damage in α1-antitrypsin deficiency
    BAL and tissue markers show evidence of recurrent alveolar haemorrhage in α1-antitrypsin-deficient subjects, likely driven by unopposed neutrophil elastase, causing the release of free haem, and subsequent pro-inflammatory activation and oxidative damage
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Latest Articles

  • Burden of Refractory and Unexplained Chronic Cough on Patients’ Life: a cohort study
    Luis Puente-Maestu, Ignacio Dávila, Santiago Quirce, Astrid Crespo-Lessmann, Eva Martínez-Moragón, Javier Sola, María Luisa Nieto, Francisco Javier González-Barcala, Luis Cea-Calvo, Marta Sánchez-Jareño, Cristina Rivas-Pardinas, Christian Domingo
    ERJ Open Research Jan 2023, 00425-2023; DOI: 10.1183/23120541.00425-2023
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    Gina Parcesepe, Richard J Allen, Beatriz Guillen-Guio, Samuel Moss, R Gisli Jenkins, Louise V Wain
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    Sarah Alamer, Anna Robinson-Barellla, Hamde Nazar, Andy Husband
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    Kentaro Hata, Toyoshi Yanagihara, Keisuke Matsubara, Kazufumi Kunimura, Daisuke Eto, Kunihiro Suzuki, Kazuya Tsubouchi, Satoshi Ikegame, Yoshinori Fukui, Isamu Okamoto
    ERJ Open Research Jan 2023, 00500-2023; DOI: 10.1183/23120541.00500-2023
  • Long-term efficacy of dupilumab in severe asthma by baseline oral corticosteroid dose
    Christian Domingo, Klaus F. Rabe, David Price, Guy Brusselle, Michael E. Wechsler, Changming Xia, Nami Pandit-Abid, Rebecca Gall, Paul J. Rowe, Yamo Deniz, Juby A. Jacob-Nara, Amr Radwan
    ERJ Open Research Jan 2023, 00056-2023; DOI: 10.1183/23120541.00056-2023
  • Clinical characteristics of chylothorax: results from the International Collaborative Effusion (ICE) database
    José M. Porcel, Silvia Bielsa, Carmen Civit, Avinash Aujayeb, Julius Janssen, Uffe Bodtger, Katrine Fjaellegaard, Jesper Koefod Petersen, Hugh Welch, Jenny Symonds, Michael A. Mitchell, Elżbieta Magdalena Grabczak, Mohamed Ellayeh, Dinesh Addala, John M Wrightson, Najib M Rahman, Mohammed Munavvar, Coenraad FN Koegelenberg, Gonzalo Labarca, Federico Mei, Nick Maskell, Rahul Bhatnagar
    ERJ Open Research Jan 2023, 00091-2023; DOI: 10.1183/23120541.00091-2023
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About ERJ Open Research

ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. It has a Journal Impact Factor of 4.6.

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