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A frequent phenotype for paediatric sleep apnoea: short lingual frenulum

Christian Guilleminault, Shehlanoor Huseni, Lauren Lo
ERJ Open Research 2016 2: 00043-2016; DOI: 10.1183/23120541.00043-2016
Christian Guilleminault
Stanford University Sleep Medicine Division, Redwood City, CA, USA
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  • For correspondence: cguil@stanford.edu
Shehlanoor Huseni
Stanford University Sleep Medicine Division, Redwood City, CA, USA
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Lauren Lo
Stanford University Sleep Medicine Division, Redwood City, CA, USA
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  • FIGURE 1
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    FIGURE 1

    Measurement of the frenulum using the commercially available Quick Tongue Tie Assessment Kit (Neo Health Services Inc., Coconut Creek, FL, USA). a) Normal frenulum [9]; b) free tongue [7]. Complete clinical protocols for lingual frenulum investigations for infants [13] and children–adolescents [25] have been published.

  • FIGURE 2
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    FIGURE 2

    a–h) Examples of short frenula in children and teenagers. Consideration was given only to shortness of the frenulum and not difference in presentation of the frenulum. Histological studies have shown that different types of fibres may be present, depending on the individual. Short frenula were found in e) a 40-year-old mother and f) her 14-year-old daughter. The other subjects are aged 3–16 years. All subjects have obstructive sleep apnoea syndrome.

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  • TABLE 1

    Demographic and clinical presentation of children with obstructive sleep apnoea syndrome with short and normal lingual frenula

    SubjectsShort frenulumNormal frenulump-value
    Subjects1506387
    Age years mean±sd (n/N)1509.88±3.21 (63/150)8.05±3.59 (87/150)0.0015
    Females5829/63 (46)29/87 (33)0.1288
    Symptoms
     Fatigue14761/63 (96)86/87 (98)0.5725
     EDS7335/63 (55)38/87 (43)0.1859
     Inattention/hyperactivity9043/63 (68)47/87 (54)0.0926
    Anatomy
     High and narrow palatal vault6356/70 (80)7/80 (8.75)0.0001
     Friedman tonsil score1501.8±0.93.2±0.90.0001
     Mallampati scale score1503.4±0.62.9±0.70.0001
    Past medical history150
     Difficulty sucking60
     Difficulty swallowing40
     Speech problems310
    • Data are presented as n, n/N (%) or mean±sd, unless otherwise stated. Feeding and swallowing difficulties were poorly recollected, except in a few cases where the problem was mentioned as “important”; the speech problems were better recalled and were described as “lisp”, “stutter” or having led to speech therapy, mostly in school (n=15). Despite speech therapy, the presence of a short lingual frenulum had not been investigated or mentioned to parents. EDS: excessive daytime sleepiness.

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A frequent phenotype for paediatric sleep apnoea: short lingual frenulum
Christian Guilleminault, Shehlanoor Huseni, Lauren Lo
ERJ Open Research Jul 2016, 2 (3) 00043-2016; DOI: 10.1183/23120541.00043-2016

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A frequent phenotype for paediatric sleep apnoea: short lingual frenulum
Christian Guilleminault, Shehlanoor Huseni, Lauren Lo
ERJ Open Research Jul 2016, 2 (3) 00043-2016; DOI: 10.1183/23120541.00043-2016
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