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Breastfeeding and respiratory tract infections during the first 2 years of life

Jingying Wang, Alban Ramette, Maja Jurca, Myrofora Goutaki, Caroline S. Beardsmore, Claudia E. Kuehni
ERJ Open Research 2017 3: 00143-2016; DOI: 10.1183/23120541.00143-2016
Jingying Wang
1Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
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Alban Ramette
1Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
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Maja Jurca
1Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
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Myrofora Goutaki
1Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
2Paediatric Respiratory Medicine, Children's University Hospital of Bern, Bern, Switzerland
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Caroline S. Beardsmore
3Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK
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Claudia E. Kuehni
1Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
2Paediatric Respiratory Medicine, Children's University Hospital of Bern, Bern, Switzerland
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Tables

  • TABLE 1

    Associations between breastfeeding duration and respiratory tract infections

    Breastfeeding duration as categorical exposureUnadjusted (n=4040)Adjusted# (n=3963)
    OR (95% CI)p-valueOR (95% CI)p-value
    Frequent colds
     No breastfeeding1.001.00
     ≤6 months0.97 (0.82–1.16)0.7491.00 (0.83–1.21)0.985
     >6 months0.99 (0.80–1.24)0.9581.01 (0.80–1.27)0.953
    Ear infections
     No breastfeeding1.001.00
     ≤6 months0.91 (0.80–1.05)0.1980.97 (0.84–1.13)0.710
     >6 months0.84 (0.70–0.99)0.0480.88 (0.73–1.06)0.177
    Croup
     No breastfeeding1.001.00
     ≤6 months0.92 (0.71–1.19)0.5230.95 (0.72–1.26)0.738
     >6 months0.92 (0.66–1.28)0.6120.86 (0.60–1.23)0.408
    Bronchiolitis
     No breastfeeding1.001.00
     ≤6 months0.79 (0.64–0.97)0.0280.89 (0.70–1.12)0.316
     >6 months0.68 (0.51–0.91)0.0090.72 (0.52–0.97)0.034
    Pneumonia
     No breastfeeding1.001.00
     ≤6 months1.28 (0.70–2.35)0.4211.44 (0.76–2.73)0.260
     >6 months1.18 (0.55–2.55)0.6751.11 (0.48–2.55)0.810
    Breastfeeding duration as continuous exposureUnadjusted (n=2286)Adjusted# (n=2248)
    OR¶ (95% CI)p-valueOR¶ (95% CI)p-value
    Frequent colds
     No breastfeeding1.001.00
     Breastfeeding (per month)1.00 (0.98–1.03)0.7361.00 (0.98–1.03)0.734
    Ear infections
     No breastfeeding1.001.00
     Breastfeeding (per month)0.99 (0.97–1.01)0.2770.99 (0.97–1.01)0.408
    Croup
     No breastfeeding1.001.00
     Breastfeeding (per month)1.00 (0.96–1.04)0.8270.99 (0.95–1.03)0.571
    Bronchiolitis
     No breastfeeding1.001.00
     Breastfeeding (per month)0.95 (0.91–0.99)0.0160.96 (0.92–1.00)0.054
    Pneumonia
     No breastfeeding1.001.00
     Breastfeeding (per month)1.00 (0.91–1.10)0.9721.00 (0.90–1.11)0.991

    Baseline group: children that had never been breastfed. #: for sex, ethnicity, socioeconomic status (Townsend deprivation score), perinatal factors (gestational age, birthweight, birth season), environmental factors (pre- and post-natal maternal smoking, number of older siblings, day care attendance) and family history of asthma, hay fever and bronchitis. ¶: ORs here are presented as odds with every 1-month increase of breastfeeding duration compared to odds of children who had never been breastfed.

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    Breastfeeding and respiratory tract infections during the first 2 years of life
    Jingying Wang, Alban Ramette, Maja Jurca, Myrofora Goutaki, Caroline S. Beardsmore, Claudia E. Kuehni
    ERJ Open Research Apr 2017, 3 (2) 00143-2016; DOI: 10.1183/23120541.00143-2016

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    Breastfeeding and respiratory tract infections during the first 2 years of life
    Jingying Wang, Alban Ramette, Maja Jurca, Myrofora Goutaki, Caroline S. Beardsmore, Claudia E. Kuehni
    ERJ Open Research Apr 2017, 3 (2) 00143-2016; DOI: 10.1183/23120541.00143-2016
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