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Compliance after switching from CPAP to ASV: big data analysis

Jean-Louis Pepin, Holger Woehlre, Dongquan Liu, Jeff Armitstea, Peter Cistulli, Adam Benjafield, Atul Malhotra
ERJ Open Research 2017 3: P45; DOI: 10.1183/23120541.sleepandbreathing-2017.P45
Jean-Louis Pepin
1CHU de Grenoble, Grenoble, France
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Holger Woehlre
2Sleep & Ventilation Center Blaubeuren, Ulm, Germany
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Dongquan Liu
3ResMed Asia Ltd, Singapore
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Jeff Armitstea
4ResMed Science Center, Sidney, Australia
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Peter Cistulli
5Charles Perkins Centre, University of Sydney, Sidney, Australia
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Adam Benjafield
6ResMed Science, Center, ResMed, Corp., San Diego, USA
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Atul Malhotra
6ResMed Science, Center, ResMed, Corp., San Diego, USA
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Abstract

Background Compliance with positive airway pressure (PAP) is essential for the benefits of therapy to be realised. This big data analysis investigated 90-day compliance in patients receiving CPAP and/or adaptive servo-ventilation (ASV).

Methods Telemonitoring data were obtained from a US PAP database. Eligible patients were a 30% random sample who started PAP from 1 Jan to 2 Oct 2015. All received PAP with an AirSense/AirCurve 10 device (ResMed) and had ?1 session with use ?1h. Compliance and device usage were determined in 3 patient groups: started on CPAP, stayed on CPAP (CPAP-only); started on ASV, stayed on ASV (ASV-only); switched from CPAP to ASV (switch). Compliance was defined as device use for ?4h on 70% of nights during a consecutive 30-day period anytime during the first 90 days.

Results 198,895 patients were included; 189,724, 8,957 and 214 in the CPAP-only, ASV-only and switch groups. Patients in the ASV-only and switch groups were significantly older than CPAP-only patients. Patients who switched from CPAP to ASV had the highest residual apnea-hypopnea index (AHI) at day 1 (17.41/h vs 3.67/h and 5.30/h in the CPAP-only and ASV-only groups, respectively; p<0.001). This was also the case for AHI at week 1, and average AHI from day 1–90. At 90 days, compliance rates were 73.8% in the CPAP-only group and 73.2% in the ASV-only group. In the switch group, CPAP compliance before the switch was 62.1% but this improved to 74.8% after the switch to ASV.

Conclusion Real-world compliance with PAP over the first 90 days was good. For patients with a high AHI at CPAP initiation, switching to ASV was associated with better compliance, with a rate that was similar to that achieved with single mode therapies.

  • Copyright ©the authors 2017
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Compliance after switching from CPAP to ASV: big data analysis
Jean-Louis Pepin, Holger Woehlre, Dongquan Liu, Jeff Armitstea, Peter Cistulli, Adam Benjafield, Atul Malhotra
ERJ Open Research Apr 2017, 3 (suppl 1) P45; DOI: 10.1183/23120541.sleepandbreathing-2017.P45

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Compliance after switching from CPAP to ASV: big data analysis
Jean-Louis Pepin, Holger Woehlre, Dongquan Liu, Jeff Armitstea, Peter Cistulli, Adam Benjafield, Atul Malhotra
ERJ Open Research Apr 2017, 3 (suppl 1) P45; DOI: 10.1183/23120541.sleepandbreathing-2017.P45
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