ERJ Open Research: 4 (1)

01 January 2018; volume 4, issue 1

Breaking news

Open Access
Influenza news from the frontline: what's happening?
Anita K. Simonds

ERJ Open Res 4: 00020-2018; DOI: 10.1183/23120541.00020-2018 Published 16 February 2018

Editorials

Open Access
Advance care planning in severe COPD: it is time to engage with the future
Stefan Andreas, Bernd Alt-Epping

ERJ Open Res 4: 00009-2018; DOI: 10.1183/23120541.00009-2018 Published 16 February 2018
Open Access
Let research leave you breathless, not physical exercise!
Matteo Bonini, Omar S. Usmani

ERJ Open Res 4: 00010-2018; DOI: 10.1183/23120541.00010-2018 Published 20 March 2018

Course report

Open Access
The European Respiratory Society course on acute respiratory pandemics: how to plan for and manage them
Adekunle Olatayo Adeoti, Sierk Marbus

ERJ Open Res 4: 00156-2017; DOI: 10.1183/23120541.00156-2017 Published 13 February 2018

Messages from Milan

Open Access
European Respiratory Society International Congress 2017: highlights from the Clinical Assembly
Nicolas Kahn, Evgeni Mekov, Laura Fregonese, Vasileios Andrianopoulos, Frits M.E. Franssen, Aleksandar Grgic, Johan Coolen, Peter I. Bonta, Daniela Gompelmann, Jouke T. Annema, Paola Faverio, Francesco Bonella, Luke Daines, Hillary Pinnock, Janwillem Kocks, Felix Herth

ERJ Open Res 4: 00134-2017; DOI: 10.1183/23120541.00134-2017 Published 10 January 2018
Open Access
Research highlights from the 2017 ERS International Congress: airway diseases in focus
Cecilia Andersson, Sara J. Bonvini, Peter Horvath, Eduardo Marquez, Imran Satia, Paul Kirkham, Florence Schleich, Marco Idzko, Reinoud Gosens, Jose Luis Lopez-Campos, Apostolos Bossios, Omar Usmani, Antonio Spanevello, Ian M. Adcock, Alexander G. Mathioudakis

ERJ Open Res 4: 00163-2017; DOI: 10.1183/23120541.00163-2017 Published 13 March 2018

Series

Open Access
COPD: time to improve its taxonomy?
Bartolomé R. Celli, Alvar Agustí

ERJ Open Res 4: 00132-2017; DOI: 10.1183/23120541.00132-2017 Published 16 February 2018

Review

Open Access
An algorithmic approach for the treatment of severe uncontrolled asthma
Eleftherios Zervas, Konstantinos Samitas, Andriana I. Papaioannou, Petros Bakakos, Stelios Loukides, Mina Gaga

ERJ Open Res 4: 00125-2017; DOI: 10.1183/23120541.00125-2017 Published 6 March 2018

Study protocol

Open Access
Rationale and design of the screening of pulmonary hypertension in systemic lupus erythematosus (SOPHIE) study
Duo Huang, Yang-Yang Cheng, Pak-Hei Chan, Jojo Hai, Kai-Hang Yiu, Hung-Fat Tse, Ka-Lam Wong, Katherine Fan, Ying Wah Li, Woon-Leung Ng, Cheuk-Wan Yim, Cheuk-hon John Wong, Lai-Shan Tam, Priscilla C.H. Wong, Chi-Yuen Wong, Chup-Hei Ho, Alexander M.H. Leung, Chi-Chiu Mok, Ho Lam, Chak-Sing Lau, Tommy Cheung, Carmen Ho, Sharon W.Y. Law, Esther W. Chan, Li-Xue Yin, Wen-Sheng Yue, Toi Meng Mok, Mario Alberto Evora, Chung-Wah Siu

ERJ Open Res 4: 00135-2017; DOI: 10.1183/23120541.00135-2017 Published 6 March 2018

Original articles

Open Access
Pleural tuberculosis: medical thoracoscopy greatly increases the diagnostic accuracy
Angelo Gianni Casalini, Pier Anselmo Mori, Maria Majori, Miriam Anghinolfi, Enrico Maria Silini, Letizia Gnetti, Federica Motta, Sandra Larini, Sara Montecchini, Roberta Pisi, Adriana Calderaro

ERJ Open Res 4: 00046-2017; DOI: 10.1183/23120541.00046-2017 Published 5 January 2018
Open Access
Effects of umeclidinium/vilanterol on exercise endurance in COPD: a randomised study
John H. Riley, Chris J. Kalberg, Alison Donald, David A. Lipson, Muhammad Shoaib, Lee Tombs

ERJ Open Res 4: 00073-2017; DOI: 10.1183/23120541.00073-2017 Published 5 January 2018
Open Access
The pronounced high expression of discoidin domain receptor 2 in human interstitial lung diseases
Huan Bian, Xiaowei Nie, Xin Bu, Feng Tian, Libo Yao, Jingyu Chen, Jin Su

ERJ Open Res 4: 00138-2016; DOI: 10.1183/23120541.00138-2016 Published 19 January 2018
Open Access
Upper airway involvement in bronchiectasis is marked by early onset and allergic features
Michal Shteinberg, Najwan Nassrallah, Jenny Jrbashyan, Nechama Uri, Nili Stein, Yochai Adir

ERJ Open Res 4: 00115-2017; DOI: 10.1183/23120541.00115-2017 Published 19 January 2018
Open Access
Decrease in pulmonary function and oxygenation after lung resection
Barbara Cristina Brocki, Elisabeth Westerdahl, Daniel Langer, Domingos S.R. Souza, Jan Jesper Andreasen

ERJ Open Res 4: 00055-2017; DOI: 10.1183/23120541.00055-2017 Published 19 January 2018
Open Access
Incidence and predictive factors of lung cancer in patients with idiopathic pulmonary fibrosis
Eisuke Kato, Noboru Takayanagi, Yotaro Takaku, Naho Kagiyama, Tetsu Kanauchi, Takashi Ishiguro, Yutaka Sugita

ERJ Open Res 4: 00111-2016; DOI: 10.1183/23120541.00111-2016 Published 2 February 2018
Open Access
Supporting patients self-managing respiratory health: a qualitative study on the impact of the Breathe Easy voluntary group network
Ferhana Hashem, Rowena Merritt

ERJ Open Res 4: 00076-2017; DOI: 10.1183/23120541.00076-2017 Published 9 February 2018
Open Access
Real-life experience of ceritinib in crizotinib-pretreated ALK⁺ advanced non-small cell lung cancer patients
Jacques Cadranel, Alexis B. Cortot, Hervé Lena, Bertrand Mennecier, Pascal Do, Eric Dansin, Julien Mazieres, Christos Chouaid, Maurice Perol, Fabrice Barlesi, Gilles Robinet, Sylvie Friard, Luc Thiberville, Clarisse Audigier-Valette, Alain Vergnenegre, Virginie Westeel, Khemaies Slimane, Alexandru Buturuga, Denis Moro-Sibilot, Benjamin Besse

ERJ Open Res 4: 00058-2017; DOI: 10.1183/23120541.00058-2017 Published 13 February 2018
Open Access
Integrated respiratory and palliative care may improve outcomes in advanced lung disease
Natasha Smallwood, Michelle Thompson, Matthew Warrender-Sparkes, Peter Eastman, Brian Le, Louis Irving, Jennifer Philip

ERJ Open Res 4: 00102-2017; DOI: 10.1183/23120541.00102-2017 Published 16 February 2018
Open Access
The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials
Rachel E. Foong, Alana J. Harper, Billy Skoric, Louise King, Lidija Turkovic, Miriam Davis, Charles C. Clem, Tim Rosenow, Stephanie D. Davis, Sarath Ranganathan, Graham L. Hall, Kathryn A. Ramsey

ERJ Open Res 4: 00094-2017; DOI: 10.1183/23120541.00094-2017 Published 16 February 2018
Open Access
OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport
Khalide Azam, Nureisha Cadir, Carla Madeira, Stephen H. Gillespie, Wilber Sabiiti

ERJ Open Res 4: 00074-2017; DOI: 10.1183/23120541.00074-2017 Published 16 February 2018
Open Access
Do-not-resuscitate orders as part of advance care planning in patients with COPD
Jo Raskin, Kristina Vermeersch, Stephanie Everaerts, Pascal Van Bleyenbergh, Wim Janssens

ERJ Open Res 4: 00116-2017; DOI: 10.1183/23120541.00116-2017 Published 16 February 2018
Open Access
Leaks during multiple-breath washout: characterisation and influence on outcomes
Nina Lenherr, Kathryn A. Ramsey, Kerstin Jost, Linn Hornwall, Florian Singer, Sophie Yammine, Philipp Latzin

ERJ Open Res 4: 00012-2017; DOI: 10.1183/23120541.00012-2017 Published 23 February 2018
Open Access
Factors influencing readthrough therapy for frequent cystic fibrosis premature termination codons
Iwona Pranke, Laure Bidou, Natacha Martin, Sandra Blanchet, Aurélie Hatton, Sabrina Karri, David Cornu, Bruno Costes, Benoit Chevalier, Danielle Tondelier, Emmanuelle Girodon, Matthieu Coupet, Aleksander Edelman, Pascale Fanen, Olivier Namy, Isabelle Sermet-Gaudelus, Alexandre Hinzpeter

ERJ Open Res 4: 00080-2017; DOI: 10.1183/23120541.00080-2017 Published 23 February 2018
Open Access
Reproducibility of hypercapnic ventilatory response measurements with steady-state and rebreathing methods
Denise C. Mannée, Timon M. Fabius, Michiel Wagenaar, Michiel M.M. Eijsvogel, Frans H.C. de Jongh

ERJ Open Res 4: 00141-2017; DOI: 10.1183/23120541.00141-2017 Published 23 February 2018
Open Access
Ventilator flow data predict bronchopulmonary dysplasia in extremely premature neonates
Mariann H. Bentsen, Trond Markestad, Thomas Halvorsen

ERJ Open Res 4: 00099-2017; DOI: 10.1183/23120541.00099-2017 Published 13 March 2018
Open Access
The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites
Elena K. Schneider, Rachel M. McQuade, Vincenzo C. Carbone, Felisa Reyes-Ortega, John W. Wilson, Brenda Button, Ayame Saito, Daniel P. Poole, Daniel Hoyer, Jian Li, Tony Velkov

ERJ Open Res 4: 00127-2017; DOI: 10.1183/23120541.00127-2017 Published 13 March 2018
Open Access
Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis
Alice C-H. Chen, Hai B. Tran, Yang Xi, Stephanie T. Yerkovich, Katherine J. Baines, Susan J. Pizzutto, Melanie Carroll, Avril A.B. Robertson, Matthew A. Cooper, Kate Schroder, Jodie L. Simpson, Peter G. Gibson, Greg Hodge, Ian B. Masters, Helen M. Buntain, Helen L. Petsky, Samantha J. Prime, Anne B. Chang, Sandra Hodge, John W. Upham

ERJ Open Res 4: 00130-2017; DOI: 10.1183/23120541.00130-2017 Published 23 March 2018
Open Access
Multidimensional fatigue in pulmonary hypertension: prevalence, severity and predictors
Todd M. Tartavoulle, Aryn C. Karpinski, Andrew Aubin, Benzi M. Kluger, Oliver Distler, Lesley Ann Saketkoo

ERJ Open Res 4: 00079-2017; DOI: 10.1183/23120541.00079-2017 Published 23 March 2018
Open Access
Physicians' perspectives on communication and decision making in clinical encounters for treatment of latent tuberculosis infection
Claudia C. Dobler, Sinthia Bosnic-Anticevich, Carol L. Armour

ERJ Open Res 4: 00146-2017; DOI: 10.1183/23120541.00146-2017 Published 23 March 2018

Original research letters

Open Access
Cytomegalovirus-associated pulmonary exacerbation in patients with cystic fibrosis
Akhil Sawant, Giulia Spoletini, Paul Whitaker, Christine Etherington, Ian Clifton, Daniel Peckham

ERJ Open Res 4: 00111-2017; DOI: 10.1183/23120541.00111-2017 Published 10 January 2018
Open Access
Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing
Niccolò Riccardi, Barbara Giannini, Maria Lucia Borghesi, Lucia Taramasso, Elena Cattaneo, Giovanni Cenderello, Federica Toscanini, Mauro Giacomini, Emanuele Pontali, Giovanni Cassola, Claudio Viscoli, Antonio Di Biagio

ERJ Open Res 4: 00108-2017; DOI: 10.1183/23120541.00108-2017 Published 2 February 2018
Open Access
An educational initiative to improve the team-based care of patients with idiopathic pulmonary fibrosis
Evans R. Fernández Pérez, Pearlanne Zelarney, Shirley Thomas, Deborah A. Shoop, Jessica L. Munson, Kelsey D. Johnson, Matthew E. Stern, Sarah Meadows

ERJ Open Res 4: 00093-2017; DOI: 10.1183/23120541.00093-2017 Published 16 February 2018
Open Access
Effect of cladribine therapy on lung cysts in pulmonary Langerhans cell histiocytosis
Mouhamad Nasser, Julie Traclet, Vincent Cottin

ERJ Open Res 4: 00089-2017; DOI: 10.1183/23120541.00089-2017 Published 23 February 2018
Open Access
The annual prognostic ability of FACED and E-FACED scores to predict mortality in patients with bronchiectasis
David de la Rosa Carrillo, Rodrigo Athanazio, Rosa Maria Girón Moreno, Luis Máiz Carro, Casilda Olveira, Javier de Gracia, Montserrat Vendrell, Concepción Prados Sánchez, Georgina Gramblicka, Monica Corso Pereira, Fernando Lundgren, Mara Fernandes De Figueiredo, Francisco Arancibia, Samia Rached, Miguel-Angel Martínez-Garcia

ERJ Open Res 4: 00139-2017; DOI: 10.1183/23120541.00139-2017 Published 6 March 2018
Open Access
RON tyrosine kinase mutations in brain metastases from lung cancer
Melissa Milan, Silvia Benvenuti, Alice Maria Balderacchi, Anna Rita Virzì, Alessandra Gentile, Rebecca Senetta, Paola Cassoni, Paolo Maria Comoglio, Giulia Maria Stella

ERJ Open Res 4: 00083-2017; DOI: 10.1183/23120541.00083-2017 Published 6 March 2018
Open Access
Pseudoneutropenia in lymphangioleiomyomatosis (LAM) patients receiving sirolimus: evaluation in a 100 patient cohort
Vissagan Gopalakrishnan, Amanda M. Jones, Patricia Julien-Williams, Tania Machado, Robert L. Danner, Jeffrey J. Swigris, Robert Paine, Jay N. Lozier, Joel Moss

ERJ Open Res 4: 00121-2017; DOI: 10.1183/23120541.00121-2017 Published 20 March 2018
Open Access
Peripheral alveolar nitric oxide concentration reflects alveolar inflammation in autoimmune pulmonary alveolar proteinosis
Taizou Hirano, Shinya Ohkouchi, Naoki Tode, Makoto Kobayashi, Manabu Ono, Teruyuki Satoh, Yoichiro Mitsuishi, Akira Watanabe, Masao Tabata, Toshiya Irokawa, Hiromasa Ogawa, Hisatoshi Sugiura, Toshiaki Kikuchi, Keiichi Akasaka, Ryushi Tazawa, Yoshikazu Inoue, Koh Nakata, Hajime Kurosawa, Masakazu Ichinose

ERJ Open Res 4: 00071-2017; DOI: 10.1183/23120541.00071-2017 Published 23 March 2018

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