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Accumulating physical activity in at least 10-minute bouts predicts better lung function after 3-years in adults with cystic fibrosis

Narelle S. Cox, Jennifer A. Alison, Brenda M. Button, John W. Wilson, Judith M. Morton, Anne E. Holland
ERJ Open Research 2018 4: 00095-2017; DOI: 10.1183/23120541.00095-2017
Narelle S. Cox
1Discipline of Physiotherapy, La Trobe University, Melbourne, Australia
2Institute for Breathing and Sleep, Melbourne, Australia
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  • For correspondence: n.cox@latrobe.edu.au
Jennifer A. Alison
3Discipline of Physiotherapy, Faculty of Health Sciences, University of Sydney, Sydney, Australia
4Dept of Physiotherapy, Royal Prince Alfred Hospital, Camperdown, Australia
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Brenda M. Button
5Dept of Physiotherapy, Alfred Hospital, Melbourne, Australia
6Dept of Medicine, Alfred Campus, Monash University, Melbourne, Australia
7Dept of Respiratory Medicine, Alfred Hospital, Melbourne, Australia
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John W. Wilson
6Dept of Medicine, Alfred Campus, Monash University, Melbourne, Australia
7Dept of Respiratory Medicine, Alfred Hospital, Melbourne, Australia
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Judith M. Morton
8Dept of Respiratory Medicine, Monash Health, Clayton, Australia
9Dept of Medicine, Monash Campus, Monash University, Clayton, Australia
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Anne E. Holland
1Discipline of Physiotherapy, La Trobe University, Melbourne, Australia
2Institute for Breathing and Sleep, Melbourne, Australia
5Dept of Physiotherapy, Alfred Hospital, Melbourne, Australia
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Tables

  • TABLE 1

    Demographic details and clinical outcomes relative to physical activity performance

    ≥30MVPA<30MVPAMVPA-BoutsMVPA-No Bouts
    Baseline
     Subjects33282140
     Male:female22:1110:1814:722:18
     Age years29.9±632.6±1029.5±632.0±9
     BMI kg·m−221.8±1.822.6±3.621.9±2.222.3±3.1
     Pancreatic insufficiency31272037
     CF-related diabetes7759
     FEV1 L2.8±0.92.3±1.02.9±1.02.3±0.9
     FEV1 % predicted69±1865±2371±2064±20
    1-year follow-up
     FEV1 L2.8±0.92.2±1.12.9±0.92.3±1.0
     FEV1 % predicted69±1964±2672±2163±23
     Annual change in FEV1 L−0.01±0.2−0.03±0.20.02±0.2−0.04±0.2
     Hospitalisation frequency
      01791313
      1–21113617
      >256210
     Total hospitalisations, median (IQR)0 (0–2)1.5 (0–2)0 (0–2)1 (0–2)
     Total hospital days, median (IQR)0 (0–19)27 (0–49)0 (0–25)12 (0–44)
    3-year follow-up
     Complete cases29241834
     Male: Female21:88:1613:515:19
     FEV1 L2.7±1.02.2±1.12.9±1.02.2±1.0
     FEV1 % predicted66±2063±2871±2161±25
     Annual change FEV1 L−0.03±0.12−0.05±0.090.01±0.1−0.07±0.1
     Hospitalisation frequency
      05447
      1–210577
      >21415720
     Total hospitalisations, median (IQR)2 (1–7)4 (1–7)2 (0.8–6)4 (1–7)
     Total hospital days, median (IQR)19 (4–100)51 (10–115)17 (6–92)44 (9–119)

    Data are presented as n or mean±sd, unless otherwise stated. MVPA: moderate-vigorous physical activity; ≥30MVPA: spent at least 30 min in MVPA daily; <30MVPA: did not achieve at least 30 min MVPA daily; MVPA-Bouts: achieved 30 min MVPA in bouts of ≥10 min duration; MVPA-No Bouts: did not achieve 30 min MVPA in bouts of ≥10 min duration; BMI: body mass index; CF: cystic fibrosis; FEV1: forced expiratory volume in 1 s; IQR: interquartile range.

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    Accumulating physical activity in at least 10-minute bouts predicts better lung function after 3-years in adults with cystic fibrosis
    Narelle S. Cox, Jennifer A. Alison, Brenda M. Button, John W. Wilson, Judith M. Morton, Anne E. Holland
    ERJ Open Research Apr 2018, 4 (2) 00095-2017; DOI: 10.1183/23120541.00095-2017

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    Accumulating physical activity in at least 10-minute bouts predicts better lung function after 3-years in adults with cystic fibrosis
    Narelle S. Cox, Jennifer A. Alison, Brenda M. Button, John W. Wilson, Judith M. Morton, Anne E. Holland
    ERJ Open Research Apr 2018, 4 (2) 00095-2017; DOI: 10.1183/23120541.00095-2017
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