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Dynamic hyperinflation during the 6-min walk test in severely asthmatic subjects

Alida Benfante, Fabiano Di Marco, Silvia Terraneo, Stefano Centanni, Nicola Scichilone
ERJ Open Research 2018 4: 00143-2017; DOI: 10.1183/23120541.00143-2017
Alida Benfante
1Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Pneumologia, University of Palermo, Palermo, Italy
3These two authors contributed equally to this work
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Fabiano Di Marco
2Respiratory Unit, Ospedale San Paolo, ASST Santi Paolo e Carlo, Dept of Health Sciences, Università degli Studi di Milano, Milan, Italy
3These two authors contributed equally to this work
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Silvia Terraneo
2Respiratory Unit, Ospedale San Paolo, ASST Santi Paolo e Carlo, Dept of Health Sciences, Università degli Studi di Milano, Milan, Italy
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Stefano Centanni
2Respiratory Unit, Ospedale San Paolo, ASST Santi Paolo e Carlo, Dept of Health Sciences, Università degli Studi di Milano, Milan, Italy
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Nicola Scichilone
1Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Pneumologia, University of Palermo, Palermo, Italy
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    FIGURE 1

    Changes in inspiratory capacity (IC) during the 6-min walk test. COPD: chronic obstructive pulmonary disease. p<0.0001 for both groups.

  • FIGURE 2
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    FIGURE 2

    Association between changes in inspiratory capacity (IC) during the 6-min walk test and changes in the Borg scale: a) chronic obstructive pulmonary disease group and b) asthmatic group.

Tables

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  • TABLE 1

    Baseline lung functional characteristics of the study subjects

    Severe asthmatic subjectsCOPD subjectsp-value
    FEV1 % pred74±2273±220.89
    FVC % pred89±1992±220.57
    FEV1/FVC0.68±0.10.62±0.10.02
    FEF25–75% % pred40±2135±160.23
    FEF75% % pred53±2433±190.0007
    FEF50% % pred41±2238±200.57
    FEF25% % pred37±2147±230.10

    Data are presented as mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF: forced expiratory flow; FEF25–75%: FEF at 25–75% of FVC; FEF75%: FEF at 75% of FVC; FEF50%: FEF at 50% of FVC; FEF25%: FEF at 25% of FVC.

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    Dynamic hyperinflation during the 6-min walk test in severely asthmatic subjects
    Alida Benfante, Fabiano Di Marco, Silvia Terraneo, Stefano Centanni, Nicola Scichilone
    ERJ Open Research Apr 2018, 4 (2) 00143-2017; DOI: 10.1183/23120541.00143-2017

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    Dynamic hyperinflation during the 6-min walk test in severely asthmatic subjects
    Alida Benfante, Fabiano Di Marco, Silvia Terraneo, Stefano Centanni, Nicola Scichilone
    ERJ Open Research Apr 2018, 4 (2) 00143-2017; DOI: 10.1183/23120541.00143-2017
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