Figures
- FIGURE 1
Receiver operating characteristic (ROC) curve of the prediction equation for the outcome “culture-positive” (i.e. pulmonary tuberculosis). AUC: area under the ROC curve.
- FIGURE 2
Receiver operating characteristic (ROC) curve of the prediction equation for the outcome “smear-positive” (i.e. infectious pulmonary tuberculosis). AUC: area under the ROC curve.
Tables
- TABLE 1
Demographic and clinical features by pulmonary tuberculosis (TB) diagnosis status and smear status
Culture-positive Culture-negative p-value Smear-positive All others p-value Subjects 170 221 74 317 Age years 46.2±21.0 44.6±16.3 0.42 45.4±21.2 45.3±17.8 0.97 Male 90 (52.9) 111 (50.2) 0.59 41 (55.4) 160 (50.4) 0.44 Clinical characteristics mean score# Symptoms 2.7±1.14 1.1±0.58 <0.001 3.3±0.87 1.4±0.92 <0.001 Duration of symptoms 3.0±1.24 1.1±0.72 <0.001 3.5±0.89 1.6±1.2 <0.001 Absence of dyspnoea 3.7±0.60 3.9±0.22 <0.001 3.6±0.64 3.9±0.37 <0.001 Antibiotic use 1.9±1.20 1.1±0.53 <0.001 2.4±1.2 1.2±0.75 <0.001 Epidemiological risk of acquiring Mycobacterium tuberculosis infection 2.5±0.68 2.8±0.92 0.007 2.3±0.54 2.7±0.87 0.002 Risk factors for reactivation of LTBI 1.4±0.82 1.1±0.51 <0.001 1.5±0.74 1.1±0.66 <0.001 Complete blood count 2.9±0.99 2.1±0.64 <0.001 3.1±1.01 2.3±0.82 <0.001 Data are presented as n, mean±sd or n (%), unless otherwise stated. LTBI: latent TB infection. #: refers to the mean of the score, ranging from 1 to 4, characterising the association between the predictor and outcome from clinical experience.
- TABLE 2
Results from the multiple logistic regression model for culture status
aOR (95% CI) p-value Age 0.98 (0.96–1.00) 0.05 Male 1.13 (0.62–2.07) 0.67 Clinical characteristics Symptoms 1.79 (1.09–2.96) 0.02 Duration of symptoms 2.24 (1.51–3.34) <0.001 Absence of dyspnoea 0.85 (0.36–2.00) 0.71 Antibiotic use 1.16 (0.77–1.77) 0.46 Epidemiological risk of acquiring Mycobacterium tuberculosis infection 1.06 (0.74–1.51) 0.72 Risk factors for reactivation of LTBI 1.72 (1.08–2.72) 0.02 Complete blood count 2.28 (1.58–3.31) <0.001 aOR: adjusted OR; LTBI: latent tuberculosis infection.
- TABLE 3
Results from the multiple logistic regression model for infectious pulmonary tuberculosis (smear-positive, culture-positive disease)
aOR (95% CI) p-value Age 1.00 (0.98–1.02) 0.79 Male 1.23 (0.57–265) 0.59 Chest radiograph 12.34 (5.32–28.62) <0.001 Clinical characteristics Symptoms 2.91 (1.80–4.68) <0.001 Duration of symptoms 0.94 (0.60–1.46) 0.80 Absence of dyspnoea 0.62 (0.30–1.26) 0.18 Antibiotic use 1.55 (1.10–2.18) 0.01 Epidemiological risk of acquiring Mycobacterium tuberculosis infection 0.94 (0.52–1.69) 0.84 Risk factors for reactivation of LTBI 1.35 (0.86–2.14) 0.18 Complete blood count 1.45 (0.96–2.18) 0.07 aOR: adjusted OR; LTBI: latent tuberculosis infection.
Supplementary Material
Please note: supplementary material is not edited by the Editorial Office, and is uploaded as it has been supplied by the author.
Scoring matrix 00170-2017_Scoring_Matrix
Intake form 00170-2017_Intake_form
