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Sleep breathing disorders: have we reached the tipping point?

Monique C. Suarez-Giron, Valentina Isetta, Juan F. Masa, Carlos Egea, Renata L. Riha, Maria R. Bonsignore, Josep M. Montserrat
ERJ Open Research 2018 4: 00172-2017; DOI: 10.1183/23120541.00172-2017
Monique C. Suarez-Giron
1Sleep Unit, Pulmonary Service, Hospital Clinic, Barcelona, Spain
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Valentina Isetta
2Unit of Biophysics and Bioengineering, Faculty of Medicine, University of Barcelona, Barcelona, Spain
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Juan F. Masa
3Pulmonary Service, Hospital San Pedro de Alcantara, Cáceres, Spain
4Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain
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Carlos Egea
4Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain
5Sleep Unit, Respiratory Dept, Alava University Hospital IRB, Vitoria, Spain
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Renata L. Riha
6Dept of Sleep Medicine, Royal Infirmary Edinburgh, Edinburgh, UK
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Maria R. Bonsignore
7Biomedical Department of Internal and Specialistic Medicine (DiBiMIS), University of Palermo, Palermo, Italy
8Institute of Biomedicine and Molecular Immunology (IBIM), National Research Council (CNR), Palermo, Italy
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Josep M. Montserrat
1Sleep Unit, Pulmonary Service, Hospital Clinic, Barcelona, Spain
4Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain
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Abstract

Sleep medicine: a new approach http://ow.ly/qzVh30iVkWL

In recent decades, the study of sleep breathing disorders has accelerated and increased our overall knowledge of sleep disorders in general. This now represents a real challenge to the health system due to the high prevalence, morbidity and mortality with concomitant social and economic repercussions [1].

Over the last few years, with sleep apnoea having greater diffusion on social media and in professional areas, the demands of sleep care have increased exponentially; however, health system strategies have not provided an adequate response. This has resulted in the saturation of sleep units with long patient waiting times, especially at a tertiary care level. This is far removed from the usual logical consideration that in the case of a common disease, all levels of care must be involved, from primary care centres, nonreferring hospitals, specialised nursing units and administration, to homecare providers, in order to deal with patients in an appropriate and personalised way. However, this basic concept of medical care collides with what is, at present, an embarrassing reality. Global sleep disorders are not dealt with in any detail at universities and little attention is paid to them during residencies or medical training periods. In fact, a percentage of respiratory specialists have no knowledge of sleep apnoea or other associated sleep disorders [2].

As a consequence, health professionals at various medical care levels find it difficult to carry out diagnosis, treatment and follow-up or even appropriate referral. In addition, it is well known that symptoms are the most important indication for treatment but there are other deleterious effects that must be taken into account. For instance, at present, sleep apnoea syndrome (SAHS) is “stagnant” in cardiovascular patients but if we consider it as a general entity, its harmful effects may occur in other settings such as metabolic and neurocognitive disorders, renal pathology, or even cancer [3–6]. Moreover, sleep breathing disorders are not restricted to SAHS, which in noncomplex situations, can be controlled by primary care medicine, but also include breathing disorders that need noninvasive mechanical ventilation, which is likely to establish itself as a key element in the near future, thanks in part to advances in technology. However, technology itself can also be harmful if not properly used or understood, a phenomenon known as the technological labyrinth syndrome. Technology should be simple, easy to use, reliable and above all, transparent; it should not be a black box. The better it is understood, the better it will be used. Other sleep disorders should be borne in mind, such as insomnia, chronobiology, paediatric sleep disorders and sleep health, which make up an important quintet both due to their symptoms and due to the risk they represent for other diseases [7, 8]. At present, the paediatric population needs more attention, as do women with SAHS; two areas that have received minimum attention to date.

All the problems listed above are clamouring for a sea change in the way we focus on our constantly changing reality and new challenges [9]. Networking and telemedicine techniques seem to be a good option, possibly generating a cost-effective personalised form of care provision. However, this has not been universally adopted and the care provided in sleep medicine in certain countries is probably outdated [10]. As our knowledge changes in the light of new technologies, methods and research [11], so does the stability of the status quo. Another aspect to bear in mind is the fact that sleep medicine is often led by service companies, insurers or even government bodies, thus disproportionately driving practice [11, 12]. Medical care must not be a monetary concern but rather a health concern, and in relation to sleep disorders, should focus on the effect that these disorders have on the rest of the organism in health and disease. Sleep is probably even more important than exercise; for example, 2 days without proper sleep can have a more deleterious effect on health than not performing physical exercise or following an adequate diet (two of the classic elements of health).

Should a new approach to sleep medicine be based mainly on evolution, on disruption or on both? Evolution can be slow but fast disruption may be dangerous. To answer this question, a number of considerations should be made to realise that the present needs with respect to sleep in a broad spectrum are initially sufficient to adjust the necessary change, and in the context of illness and health. In order to introduce sleep into the concept of general health, it will be essential to liaise with the authorities, with all health professionals, with the population at large and with others who work to improve health through sleep. The broadcasting of regulations is also a key element.

Regarding sleep as a clinical entity, several fundamental aspects of our understanding and practice require modification. 1) Health professionals must start to adapt to new scenarios; care for sleep as an element of health in general terms must be provided by all professionals in collaboration with companies, the health authorities and universities. 2) Patient assessment must improve in order to personalise management and attempt to be mainly outpatient based. 3) Most current technologies for assessing sleep (polysomnography) should improve (new sensors, simple devices and contactless equipment) and most of them should be able to record data over several days. 4) Collaboration across different professions and medical specialties, epidemiologists, basic researchers, and biomedical engineers must become the defining premise that will allow us to learn and understand what patients and professionals need to carry our transformative action. All levels of care must be involved and technology must become simple to use, reliable and transparent regarding its algorithms and programmes.

In view of the speed of current global changes, a good example of evolution could be the application of lean methodology: continuous, linear improvement in the short term, which in fact represents a disruptive aspect. In this regard, it is essential to develop, prioritise the reasons for our projects, and think of sleep as a combination of entities that may affect other biological systems in both disease and health. These two viewpoints have led to different opinions or positions in different societies [13–15]. Perhaps it is not only a problem of urgency but above all, one of mentality and adaptation. At present, the quintet of sleep breathing disorders, insomnia, chronobiology in a broad sense, paediatrics and sleep health are the first imperative challenges to address. The different levels of care, collaboration with patients and the proper use of new technology are key elements that are essential to approach to sleep disturbances.

These points of view are those of the authors and not a position statement of the European Respiratory Society.

Footnotes

  • Conflict of interest: None declared.

  • Received December 27, 2017.
  • Accepted February 11, 2018.
  • Copyright ©ERS 2018

This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

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Sleep breathing disorders: have we reached the tipping point?
Monique C. Suarez-Giron, Valentina Isetta, Juan F. Masa, Carlos Egea, Renata L. Riha, Maria R. Bonsignore, Josep M. Montserrat
ERJ Open Research Apr 2018, 4 (2) 00172-2017; DOI: 10.1183/23120541.00172-2017

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Sleep breathing disorders: have we reached the tipping point?
Monique C. Suarez-Giron, Valentina Isetta, Juan F. Masa, Carlos Egea, Renata L. Riha, Maria R. Bonsignore, Josep M. Montserrat
ERJ Open Research Apr 2018, 4 (2) 00172-2017; DOI: 10.1183/23120541.00172-2017
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