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Children and Adults Tai Chi Study (CF-CATS2): a randomised controlled feasibility study comparing internet-delivered with face-to-face Tai Chi lessons in cystic fibrosis

Siobhán B. Carr, Patricia Ronan, Ava Lorenc, Awais Mian, Susan L. Madge, Nicola Robinson
ERJ Open Research 2018 4: 00042-2018; DOI: 10.1183/23120541.00042-2018
Siobhán B. Carr
1Department of Paediatric Respiratory Medicine, The Royal Brompton and Harefield NHS Foundation Trust, London, UK
5Both authors contributed equally
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  • ORCID record for Siobhán B. Carr
Patricia Ronan
2School of Health and Social Care, London South Bank University, London, UK
5Both authors contributed equally
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Ava Lorenc
2School of Health and Social Care, London South Bank University, London, UK
3Population Health Sciences Department, University of Bristol, Bristol, UK
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Awais Mian
2School of Health and Social Care, London South Bank University, London, UK
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Susan L. Madge
4Adult CF Department, The Royal Brompton and Harefield NHS Foundation Trust, London, UK
6Both authors contributed equally
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Nicola Robinson
2School of Health and Social Care, London South Bank University, London, UK
6Both authors contributed equally
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Figures

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  • FIGURE 1
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    FIGURE 1

    CONSORT 2010 flow diagram.

  • FIGURE 2
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    FIGURE 2

    Cystic Fibrosis Questionnaire – Revised (CFQ-R) respiratory domain results at 3-monthly intervals during the study. Each line represents an individual subject.

  • FIGURE 3
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    FIGURE 3

    Self-reported symptom scores immediately prior to each of the eight individual Tai Chi lessons for all participants. a) Trouble sleeping; b) waking due to cough; c) daytime cough; d) trouble breathing; e) stomach hurting (scale 0=never, 1=sometimes, 3=often, 4=always); f) visual analogue scores for general health and wellbeing.

Tables

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  • TABLE 1

    Baseline data at trial entry for both groups completing the 3-month Tai Chi intervention

    Face-to-faceInternet-delivered
    Subjects2218
    Male67
    Female1611
    Adults (>16 years)1511
    Teenagers (12–15 years)33
    Children (6–11 years)44
    FEV1 % pred
     <40%31
     40–70%95
     >70%1312
    Age22.75 (7.1–45.7)22.8 (6.1–51.5)
    FVC# % pred87±18.194±14.1
    FEV1# % pred69±21.677±21.8
    Height m1.56±0.21.57±0.21
    Weight kg52.5±18.352.4±17.7
    BMI kg·m−220.4±4.120.4±3.2
    CFQ-R (respiratory)64.5±25.259.4±26.5
    CFQ-R (digestion)74.8±25.475.9±28.1
    Pittsburgh Sleep Quality Index11.7±8.111.8±8
    Five Facet Mindfulness Scale (adult)112.5±14.3107.5±18.9
    CAMM (child)36.5±3.934.9±5.2

    Data are presented as n, median (range) or mean±sd. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; BMI: body mass index; CFQ-R: Cystic Fibrosis Questionnaire – Revised; CAMM: Child and Adolescent Mindfulness Measure. #: according to age, height, sex and race.

    • TABLE 2

      Linear regression coefficients for instructor questionnaire domains, with time as the independent variable

      Dependent variableIndependent variableUnstandardised coefficientsStandardised coefficientSignificance
      βStandard errorβ
      Trouble sleepingConstant0.8810.1130.000
      Time−0.0650.022−0.1600.004
      Stomach acheConstant0.7860.1140.000
      Time−0.0510.023−0.1260.025
      Daytime coughConstant1.3170.1040.000
      Time−0.0600.021−0.1610.004
      Wake with coughConstant0.6380.0960.000
      Time−0.0550.019−0.1600.004
      Trouble breathingConstant0.8430.0980.000
      Time−0.0620.019−0.1740.002
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    Children and Adults Tai Chi Study (CF-CATS2): a randomised controlled feasibility study comparing internet-delivered with face-to-face Tai Chi lessons in cystic fibrosis
    Siobhán B. Carr, Patricia Ronan, Ava Lorenc, Awais Mian, Susan L. Madge, Nicola Robinson
    ERJ Open Research Oct 2018, 4 (4) 00042-2018; DOI: 10.1183/23120541.00042-2018

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    Children and Adults Tai Chi Study (CF-CATS2): a randomised controlled feasibility study comparing internet-delivered with face-to-face Tai Chi lessons in cystic fibrosis
    Siobhán B. Carr, Patricia Ronan, Ava Lorenc, Awais Mian, Susan L. Madge, Nicola Robinson
    ERJ Open Research Oct 2018, 4 (4) 00042-2018; DOI: 10.1183/23120541.00042-2018
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